Illustration by Ian Hurley
What Are LA’s Hottest Startups of 2022? See Who VCs Picked in dot.LA’s Annual Survey
In Los Angeles—like the startup environment at large—venture funding and valuations skyrocketed in 2021, even as the coronavirus pandemic continued to surge and supply chain issues rattled the economy. The result was a startup ecosystem that continued to build on its momentum, with no shortage of companies raising private capital at billion-dollar-plus unicorn valuations.
In order to gauge the local startup scene and who’s leading the proverbial pack, we asked more than 30 leading L.A.-based investors for their take on the hottest firms in the region. They responded with more than two dozen venture-backed companies; three startups, in particular, rose above the rest as repeat nominees, while we've organized the rest by their amount of capital raised as of January, according to data from PitchBook. (We also asked VCs not to pick any of their own portfolio companies, and vetted the list to ensure they stuck to that rule.)
Without further ado, here are the 26 L.A. startups that VCs have their eyes on in 2022.
1. Whatnot ($225.4 million raised)
Whatnot was the name most often on the minds of L.A. venture investors—understandably, given its prolific fundraising year. Whatnot raised some $220 million across three separate funding rounds in 2021, on the way to a $1.5 billion valuation.
The Marina del Rey-based livestream shopping platform was founded by former GOAT product manager Logan Head and ex-Googler Grant LaFontaine. The startup made its name by providing a live auction platform for buying and selling collectables like rare Pokémon cards, and has since expanded into sports memorabilia, sneakers and apparel.
2. Boulevard ($40.3 million raised)
Boulevard’s backers include Santa Monica-based early-stage VC firm Bonfire Ventures, which focuses on B2B software startups. The Downtown-based company fits nicely within that thesis; Boulevard builds booking and payment software for salons and spas. The firm has worked with prominent brands such as Toni & Guy and HeyDay.
3. GOAT ($492.7 million)
GOAT launched in 2015 as a marketplace to help sneakerheads authenticate used Air Jordans and other collectible shoes. It has since grown at a prolific rate, expanding into apparel and accessories and exceeding $2 billion in merchandise sales in 2020. The startup sealed a $195 million funding round last summer that more than doubled its valuation, to $3.7 billion.
The Best of the Rest
VideoAmp ($578.6 raised)
Nielsen competitor VideoAmp gathers data on who's watching what across streaming services, traditional TV and social apps like YouTube. The company positions itself as an alternative to so-called "legacy" systems like Nielsen, which it says are "fragmented, riddled with complexity and inaccurate." In addition to venture funding, its total funding figure includes more than $165 million in debt financing.
Mythical Games ($269.4 million raised)
Seizing on the NFT craze, Mythical Games is building a platform that powers the growing realm of “play-to-earn games.” Backed by NBA legend Michael Jordan and Andreessen Horowitz, the Sherman Oaks-based startup’s partners include game publishers Abstraction, Creative Mobile and CCG Lab.
FloQast ($202 million raised)
FloQast founder Michael Whitmire says he got a “no” from more than 100 investors in the process of raising a seed round. Today, the accounting software company is considered a unicorn.
Nacelle ($70.8 million raised)
Nacelle produces docuseries, books, comedy albums and podcasts. The media company’s efforts include the Netflix travel series “Down To Earth with Zac Efron.”
Wave ($66 million raised)
A platform for virtual concerts, Wave has hosted performances by artists including Justin Bieber, Tinashe and The Weeknd. The company says it has raised $66 million to date from the likes of Warner Music and Tencent.
Papaya ($65.2 million raised)
Sherman Oaks-based Papaya looks to make it easier to pay “any” bill—from hospital bills to parking tickets—via its mobile app.
LeaseLock ($63.2 million raised)
Based in Marina del Rey, LeaseLock says it’s on a mission to eliminate security deposits for apartment renters.
Emotive ($58.1 million raised)
Emotive sells text message-focused marketing tools to ecommerce firms like underwear brand Parade and men's grooming company Beardbrand.
Dray Alliance ($55 million raised)
Based in Long Beach, Dray says its mission is to “modernize the logistics and trucking industry.” Its partners include Danish shipping company Maersk and toy maker Mattel.
Coco ($43 million raised)
Coco makes small pink robots on wheels (you may have seen them around town) that deliver food via a remote pilot. Its investors include Y Combinator and Silicon Valley Bank.
HiveWatch ($25 million raised)
HiveWatch develops physical security software. Its investors include former Twitter executive Dick Costollo and NBA star Steph Curry’s Penny Jar Capital.
Popshop ($24.5 million raised)
Whatnot competitor Popshop is betting that live-shopping is the future of ecommerce. The West Hollywood-based firm focuses on collectables such as trading cards and anime merchandise.
First Resonance ($19.4 million raised)
Founded by former SpaceX engineer Karan Talati, First Resonance runs a software platform for makers of electric cars and aerospace technology. Its clients include Santa Cruz-based air taxi company Joby Aviation and Alameda-based rocket company Astra.
Open Raven ($19 million raised)
Founded by Crowdstrike and Microsoft alums, Open Raven aims to protect user data. The cybersecurity firm’s investors include Kleiner Perkins and Upfront Ventures.
Fourthwall ($17 million raised)
When an actor faces the camera and speaks directly to the audience, it’s known as “breaking the fourth wall.” Named after the trope, Venice-based Fourthwall offers a website builder that’s designed for content creators.
The Non Fungible Token Company ($15 million raised)
The Non Fungible Token Company creates NFTs for musicians under the name Unblocked. Its investors include Jay Z’s Marcy Venture Partners and Shawn Mendez.
Safe Health Systems ($15 million raised)
Backed by Mayo Clinic Ventures, Safe Health develops telehealth software and offers tools for enterprises to launch their own health care apps.
Intro ($11.6 million raised)
Intro’s app lets you book video calls with experts—from celebrity stylists, to astrologists, to investors.
DASH Systems ($8.5 million raised)
With the tagline “Land the package, not the plane,” DASH Systems is a Hawthorne-based shipping company that builds hardware and software for automated airdrops.
Ettitude ($3.5 million raised)
With a focus on sustainability, Ettitude is a direct-to-consumer brand that sells bedding, bathroom textiles and sleepwear.
Afterparty ($3 million raised)
Along similar lines as Unblocked, Afterparty creates NFTs for artists and content creators such as Clay Perry and Tropix.
Heart to Heart ($0.75 million raised)
Heart to Heart is an audio-focused dating app that “lets you listen to the story behind the pictures in a profile.” Precursor Ventures led the pre-seed funding round.
Frigg (undisclosed)
Frigg makes hair and beauty products that contain cannabinoids such as CBD. The Valley Village-based company raised an undisclosed seed round in August.
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Melanie Stricklan co-founder and CEO of El Segundo-based Slingshot Aerospace, credits Helms with helping launch the startup that counts NASA among its clients. To date, the company has raised over $17 million from investors including L.A.-based Stage Venture Partners and Noname Ventures. And Helms' guidance and insight has been key to that.
"She is a pioneer. She made way for lots of other women to go to service academies and after that to pursue engineering degrees like she did," Stricklan told dot.LA. "She was the first military woman in space; the first woman to inhabit the ISS."
Slingshot Aerospace CEO Melanie Stricklan (L) and Lt. Gen. Susan Helms (R).
Stricklan, who was an Air Force military officer for over two decades before she took her degree in aeronautical space engineering to found Slingshot Aerospace in 2017, met Helms when she was Stricklan's superior in the service.
Helms' mentorship has helped Stricklan and Slingshot secure contracts from NASA, the U.S. Space Force and Air Force, as well as private contractors like Boeing, Northrop Grumman and BAE Systems.
But Helms also boosted Stricklan's confidence as she helped develop Slingshot Aerospace.
The company sells two products. Slingshot Laboratory is a mixed-reality space simulation training tool that can be used by NASA astronauts and K-12 students. Although it's still in beta mode, it's being used to train university students and the Space Force Guardians.
Then there's Slingshot Orbital, an air traffic control-like system for space travel. The system gives the government a more accurate idea of exactly what's going on up there, without having to actually send more crafts into space. Helms talks about Slingshot as if she's making a pitch for her own company. Slingshot Orbital, she said, is key to protecting the U.S. from foreign threats in space as access to the stars becomes more democratized.
"Space has now become so accessible, you have to start thinking of it as a place where conflict could take place," Helms said. "Therefore, you have to focus on it with resources and defensive strategies."
Both point out that every launch produces debris, and even an accidental collision with another country's tech could have disastrous consequences.
"Space is one of the most critical environments to make accurate decisions in, especially with all of the hundreds of new satellites increasingly filling orbits," Stricklan said. "(There's) millions of pieces of debris... It's not a hair-on-fire moment, space is big."
Both have been working in the industry to help the next generation of women in space
"We're no longer hitchhiking on Russian rockets, which I love," Stricklan said. "I love the fact that women are leading the charge," Stricklan said.
Most major aerospace firms now have a woman in their C-suite — Leanne Caret is the CEO of Boeing Defense, Space and Security; and Marilyn Hewson ran Lockheed Martin for seven years until June 2020.
"Elon gets a lot of credit for what SpaceX is doing but [its CEO] Gwynne Shotwell is terrific. When we got our ticket back as a U.S. entity to go into space on the first privatized ride, she helped Elon get there," Stricklan said.
In 2019, 75% of all the major science divisions in NASA were run by women, the organization said. This includes Sandra Cauffman, a Costa Rican-born engineer who was the first woman to be appointed to the NASA Inventions and Contributions Board in 1994.
Helms now serves as the vice president of Texas-based Astra Femina, a nonprofit dedicated to encouraging young women to pursue careers in space. Astra Femina was founded by Sandra Magnus, a former Department of Defense chief engineer and one of the few astronauts to fly on the final Space Shuttle mission in 2011.
"Some of them have to just see it to be it," Stricklan said about young women interested in the field.
Helms won't be satisfied until there's finally a woman who sets foot on the moon.
"The astronaut office was 25% female when I showed up," Helms said. "What I'm looking for are the days when it's 50/50. There's people that say, why go back to the moon if we've already been there, and my answer is well, only 50% of you have been there. When you talk about human exploration, you're talking about humans in general."
The anniversary has her feeling nostalgic.
"I'm feeling kind of sad that the spacecraft I flew on that day isn't around anymore," Helms said. " I usually don't think about the anniversary that much, but since it's the 20 year anniversary and it sets us on International Women's Day in particular, it seems especially poignant."
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Image Source: JetZero
JetZero closed a $175 million Series B to build its blended wing body “all-wing” airliner, with B Capital leading the round alongside United Airlines Ventures, Northrop Grumman, 3M Ventures, Trucks VC and RTX Ventures. The company is working toward a full-scale Demonstrator aircraft that targets at least 30% better fuel efficiency than today’s tube-and-wing jets, with a first flight planned for 2027 and a commercial Z4 airliner to follow in the early 2030s.
This is not a small bet. JetZero’s pitch is that airlines and regulators need a way to hit climate targets without waiting on sci-fi batteries or hydrogen infrastructure, and that a radically more efficient airframe is the most realistic path. It is also very much an LA story: deep aerospace talent, strategic money at the table, and a product that looks like a mashup of climate tech, defense tech and old-school manufacturing rather than another SaaS dashboard.
There is still a long way to go. The next few years are about turning simulations and wind-tunnel charts into flight data, working with regulators and proving that a manta-ray-shaped jet can slot into a world built for Boeings and Airbuses. But if JetZero gets anywhere close, it will mean that one of the most ambitious hardware bets in commercial aviation is being engineered out of Long Beach.
Scroll on for the latest LA venture rounds, fund news and acquisitions.
🤝 Venture Deals
LA Companies
- No Agent List secured $10M in private investment to launch its AI powered real estate platform ahead of a planned Spring 2026 debut. The Los Angeles based company aims to put “agent level” tools directly in the hands of buyers, sellers and vendors, offering direct access to off market properties, FSBOs, distressed assets, foreclosures, tax liens and auctions that have traditionally been gated by agents and insiders. The funding will support product development and rollout of the platform, which promises more control over transactions while using AI to surface opportunities and streamline the deal process. - learn more
- Hadrian, the Los Angeles based advanced manufacturing startup, announced new capital led by accounts advised by T. Rowe Price Associates to accelerate its push to “reindustrialize” American manufacturing. The financing, which also includes Altimeter Capital, D1 Capital Partners, StepStone Group, 1789 Capital, Founders Fund, Lux Capital, a16z, Construct Capital and others, values the company at $1.6B and will be used to expand its high-throughput factories, grow its workforce and deploy more AI, software and automation across its “factories-as-a-service” platform for aerospace, defense and critical infrastructure customers.- learn more
LA Venture Funds
- Blue Bear Capital joined Hydrosat’s $60M Series B, backing the thermal infrared satellite data company alongside lead investors Hartree Partners, Subutai Capital Partners and Space 4 Earth. The funding will help Hydrosat expand its constellation beyond its two current satellites, ramp global coverage and deepen its AI-powered “thermal intelligence” products for water resource management, agriculture, civil government and defense customers worldwide. - learn more
- Elysian Park Ventures led a $12M growth round for Diamond Kinetics, backing the Pittsburgh-based baseball tech company as it doubles down on youth development. The new capital will help Diamond Kinetics scale sidelineHD, its AI-powered youth baseball and softball live streaming and highlights platform, and expand its broader suite of training tools as MLB’s Trusted Youth Development Platform. - learn more
- MANTIS Ventures participated in Depthfirst’s $40M Series A round, backing the San Francisco based applied AI lab alongside lead investor Accel, Alt Capital, BoxGroup, Liquid 2 Ventures and SV Angel. Depthfirst is building an AI-native “General Security Intelligence” platform that uses autonomous agents to detect, triage and remediate software vulnerabilities across code and infrastructure, aiming to outpace a new wave of AI-powered cyberattacks. The fresh capital will fund R&D, go-to-market efforts and hiring as the company scales its security platform for enterprise customers. - learn more
- Cedars-Sinai Health Ventures participated in Vista AI’s $29.5M Series B, joining a slate of leading health systems backing the company’s automated MRI scanning software. The Palo Alto-based startup will use the funding to expand its FDA-cleared cardiac MRI platform to additional anatomies like brain, prostate and spine, and to roll out remote scanning services that let hospitals without in-house MRI expertise offer advanced imaging while easing backlogs and technologist shortages - learn more
- Fourward Ventures is leading a new strategic growth investment in Mermaid Gin, backing the Isle of Wight–based premium spirits brand as it accelerates expansion in the U.S. market. The round brings Fourward’s founder Will Ward onto the board as lead investor and is paired with a national distribution partnership with Southern Glazer’s Wine & Spirits, plus the appointment of longtime Moët Hennessy veteran Jim Clerkin as CEO for the U.S. push. The capital and partnership are aimed at scaling Mermaid Gin in the fast-growing U.S. super-premium gin segment while preserving its sustainability-focused, Isle of Wight roots. - learn more
- Hyperion Capital joined Haiqu’s $11M seed round, backing the quantum software startup alongside Primary Venture Partners, Collaborative Fund, Alumni Ventures, Qudit Ventures, Silicon Roundabout Ventures, Harlow Capital, Toyota Ventures and MaC Venture Capital. Haiqu is building a hardware-aware quantum operating system and middleware layer that boosts the performance of today’s noisy quantum hardware, with the new funding going toward productizing its platform and enabling near-term commercial use cases in areas like finance, cybersecurity and scientific computing. - learn more
- Sound Ventures led WitnessAI’s $58M strategic funding round, backing the Mountain View based AI security and governance platform alongside investors including Fin Capital, Qualcomm Ventures, Samsung Ventures and Forgepoint Capital Partners. The company will use the capital to accelerate global go-to-market efforts and expand its platform, which secures AI agents and models by monitoring agent activity, linking human and agent actions, and blocking prompt injection and other attacks in real time. WitnessAI also unveiled new agentic AI governance tools that give enterprises deeper observability and policy control as they scale AI agents across their operations. - learn more
- Alexandria Venture Investments joined Proxima’s oversubscribed $80M seed financing, backing the newly rebranded AI-native biotech (formerly VantAI) alongside lead investor DCVC, NVentures (NVIDIA’s venture arm), Braidwell, Roivant and others. Proxima is building a generative AI driven platform for “proximity-based medicines” that modulate protein protein interactions, including molecular glues and PROTACs, to go after historically undruggable targets in oncology, immunology and beyond. The new capital will accelerate its NeoLink structural proteomics and Neo AI model stack, and advance a pipeline of first-in-class proximity-modulating therapeutics toward the clinic. - learn more
- Clocktower Technology Ventures participated in WeatherPromise’s oversubscribed $12.8M Series A, backing the weather-guarantee startup alongside lead investor Maveron, 1Sharpe, Lerer Hippeau, Commerce Ventures, MS Transverse, Start Ventures, 1Flourish and others. WeatherPromise partners with major travel brands like Marriott, Expedia and JetBlue to offer “weather guarantees” that automatically refund trips when conditions are worse than promised, driving demand for travel, events and outdoor experiences. The new capital will accelerate product development, expand strategic partnerships and scale the platform across more consumer categories. - learn more
- MANTIS Ventures participated in Sandstone’s $10M seed round, backing the AI-native legal tech startup alongside lead investor Sequoia Capital and others. Sandstone is building an operating system for in-house legal teams that uses AI agents to route requests, draft and review contracts, and surface answers directly inside tools like email, Slack and Salesforce, turning institutional legal knowledge into reusable workflows. The new capital will help the Brooklyn-based company scale its product and grow its customer base of corporate legal departments. - learn more
- Strong Ventures participated in Hupo’s $10M Series A round, backing the Singapore-based AI sales coaching startup alongside lead investor DST Global Partners, Collaborative Fund, January Capital and Goodwater Capital. Hupo’s platform uses AI to coach frontline banking, insurance and financial services sales teams in real time, helping them ramp faster and close more deals across highly regulated markets in APAC and Europe. The new funding will support product development, expansion of its coaching features and scaling enterprise deployments as the company eyes broader international growth. - learn more
- Freeflow Ventures joined Vivere Oncotherapies’ more than $10M funding round, backing the UC Berkeley spinout alongside YK Bioventures, Pillar, Berkeley Frontier Fund and the National Cancer Institute. Vivere is developing targeted immunotherapies for “cold” solid tumors like colorectal and ovarian cancers, aiming to activate the immune system against tumors that typically evade detection and resist existing treatments. The new capital will support advancement of its proprietary bioengineering platform and pipeline of therapies for patients with few effective options today. - learn more
- Alexandria Venture Investments joined Precede Biosciences’ $63.5M Series B equity round, part of an $83.5M total financing package that also includes a $20M strategic, non-dilutive credit facility. The Boston based precision diagnostics and data company is scaling its blood-based platform, which measures target expression and pathway activity to support next-generation cancer therapies like drug, radio and immune conjugates. The new capital will help Precede meet growing demand from biopharma partners developing these precision medicines and accelerate commercialization and health system adoption. - learn more
- Alexandria Venture Investments participated in Recludix Pharma’s new equity financing round alongside Access Biotechnology, NEA and Westlake BioPartners, with additional strategic investment from Eli Lilly. The San Diego based, clinical-stage biotech will use the $123M in total equity raised to advance clinical development of its novel SH2 domain inhibitor pipeline for inflammatory diseases and to tap Lilly’s TuneLab AI/ML platform to accelerate discovery across its broader SH2 domain program. - learn more
- BOLD Capital Partners participated in MagicCube’s $10M funding round, backing the Cupertino-based software security company alongside strategic investor Verifone and other existing backers. MagicCube plans to use the capital to expand beyond its core tap-to-phone payments offering into biometrics, identity verification and AI-driven device security, while scaling its Software Defined Trust platform that delivers hardware-grade protection through software on standard mobile and IoT devices.- learn more
LA Exits
- Webalo is being acquired by Prometheus Group, which is folding the Los Angeles based “no-code for the frontline” platform into its enterprise asset management software suite. The deal will combine Webalo’s mobile, real-time workflows for frontline workers with Prometheus Group’s planning and scheduling tools, aiming to create a closed-loop digital execution platform that connects shopfloor actions directly back into systems of record like SAP and Oracle. - learn more