Illustration by Ian Hurley
What Are LA’s Hottest Startups of 2022? See Who VCs Picked in dot.LA’s Annual Survey
In Los Angeles—like the startup environment at large—venture funding and valuations skyrocketed in 2021, even as the coronavirus pandemic continued to surge and supply chain issues rattled the economy. The result was a startup ecosystem that continued to build on its momentum, with no shortage of companies raising private capital at billion-dollar-plus unicorn valuations.
In order to gauge the local startup scene and who’s leading the proverbial pack, we asked more than 30 leading L.A.-based investors for their take on the hottest firms in the region. They responded with more than two dozen venture-backed companies; three startups, in particular, rose above the rest as repeat nominees, while we've organized the rest by their amount of capital raised as of January, according to data from PitchBook. (We also asked VCs not to pick any of their own portfolio companies, and vetted the list to ensure they stuck to that rule.)
Without further ado, here are the 26 L.A. startups that VCs have their eyes on in 2022.
1. Whatnot ($225.4 million raised)
Whatnot was the name most often on the minds of L.A. venture investors—understandably, given its prolific fundraising year. Whatnot raised some $220 million across three separate funding rounds in 2021, on the way to a $1.5 billion valuation.
The Marina del Rey-based livestream shopping platform was founded by former GOAT product manager Logan Head and ex-Googler Grant LaFontaine. The startup made its name by providing a live auction platform for buying and selling collectables like rare Pokémon cards, and has since expanded into sports memorabilia, sneakers and apparel.
2. Boulevard ($40.3 million raised)
Boulevard’s backers include Santa Monica-based early-stage VC firm Bonfire Ventures, which focuses on B2B software startups. The Downtown-based company fits nicely within that thesis; Boulevard builds booking and payment software for salons and spas. The firm has worked with prominent brands such as Toni & Guy and HeyDay.
3. GOAT ($492.7 million)
GOAT launched in 2015 as a marketplace to help sneakerheads authenticate used Air Jordans and other collectible shoes. It has since grown at a prolific rate, expanding into apparel and accessories and exceeding $2 billion in merchandise sales in 2020. The startup sealed a $195 million funding round last summer that more than doubled its valuation, to $3.7 billion.
The Best of the Rest
VideoAmp ($578.6 raised)
Nielsen competitor VideoAmp gathers data on who's watching what across streaming services, traditional TV and social apps like YouTube. The company positions itself as an alternative to so-called "legacy" systems like Nielsen, which it says are "fragmented, riddled with complexity and inaccurate." In addition to venture funding, its total funding figure includes more than $165 million in debt financing.
Mythical Games ($269.4 million raised)
Seizing on the NFT craze, Mythical Games is building a platform that powers the growing realm of “play-to-earn games.” Backed by NBA legend Michael Jordan and Andreessen Horowitz, the Sherman Oaks-based startup’s partners include game publishers Abstraction, Creative Mobile and CCG Lab.
FloQast ($202 million raised)
FloQast founder Michael Whitmire says he got a “no” from more than 100 investors in the process of raising a seed round. Today, the accounting software company is considered a unicorn.
Nacelle ($70.8 million raised)
Nacelle produces docuseries, books, comedy albums and podcasts. The media company’s efforts include the Netflix travel series “Down To Earth with Zac Efron.”
Wave ($66 million raised)
A platform for virtual concerts, Wave has hosted performances by artists including Justin Bieber, Tinashe and The Weeknd. The company says it has raised $66 million to date from the likes of Warner Music and Tencent.
Papaya ($65.2 million raised)
Sherman Oaks-based Papaya looks to make it easier to pay “any” bill—from hospital bills to parking tickets—via its mobile app.
LeaseLock ($63.2 million raised)
Based in Marina del Rey, LeaseLock says it’s on a mission to eliminate security deposits for apartment renters.
Emotive ($58.1 million raised)
Emotive sells text message-focused marketing tools to ecommerce firms like underwear brand Parade and men's grooming company Beardbrand.
Dray Alliance ($55 million raised)
Based in Long Beach, Dray says its mission is to “modernize the logistics and trucking industry.” Its partners include Danish shipping company Maersk and toy maker Mattel.
Coco ($43 million raised)
Coco makes small pink robots on wheels (you may have seen them around town) that deliver food via a remote pilot. Its investors include Y Combinator and Silicon Valley Bank.
HiveWatch ($25 million raised)
HiveWatch develops physical security software. Its investors include former Twitter executive Dick Costollo and NBA star Steph Curry’s Penny Jar Capital.
Popshop ($24.5 million raised)
Whatnot competitor Popshop is betting that live-shopping is the future of ecommerce. The West Hollywood-based firm focuses on collectables such as trading cards and anime merchandise.
First Resonance ($19.4 million raised)
Founded by former SpaceX engineer Karan Talati, First Resonance runs a software platform for makers of electric cars and aerospace technology. Its clients include Santa Cruz-based air taxi company Joby Aviation and Alameda-based rocket company Astra.
Open Raven ($19 million raised)
Founded by Crowdstrike and Microsoft alums, Open Raven aims to protect user data. The cybersecurity firm’s investors include Kleiner Perkins and Upfront Ventures.
Fourthwall ($17 million raised)
When an actor faces the camera and speaks directly to the audience, it’s known as “breaking the fourth wall.” Named after the trope, Venice-based Fourthwall offers a website builder that’s designed for content creators.
The Non Fungible Token Company ($15 million raised)
The Non Fungible Token Company creates NFTs for musicians under the name Unblocked. Its investors include Jay Z’s Marcy Venture Partners and Shawn Mendez.
Safe Health Systems ($15 million raised)
Backed by Mayo Clinic Ventures, Safe Health develops telehealth software and offers tools for enterprises to launch their own health care apps.
Intro ($11.6 million raised)
Intro’s app lets you book video calls with experts—from celebrity stylists, to astrologists, to investors.
DASH Systems ($8.5 million raised)
With the tagline “Land the package, not the plane,” DASH Systems is a Hawthorne-based shipping company that builds hardware and software for automated airdrops.
Ettitude ($3.5 million raised)
With a focus on sustainability, Ettitude is a direct-to-consumer brand that sells bedding, bathroom textiles and sleepwear.
Afterparty ($3 million raised)
Along similar lines as Unblocked, Afterparty creates NFTs for artists and content creators such as Clay Perry and Tropix.
Heart to Heart ($0.75 million raised)
Heart to Heart is an audio-focused dating app that “lets you listen to the story behind the pictures in a profile.” Precursor Ventures led the pre-seed funding round.
Frigg (undisclosed)
Frigg makes hair and beauty products that contain cannabinoids such as CBD. The Valley Village-based company raised an undisclosed seed round in August.
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El Segundo’s newest unicorn is simplifying the cockpit
Skyryse raised $300M+ in a Series C at a $1.15B valuation. The round was led by Autopilot Ventures and returning investor Fidelity Management & Research Company, with participation from Qatar Investment Authority, ArrowMark Partners, Atreides, BAM Elevate, Baron Capital Group, Durable Capital Partners, Positive Sum, Rokos (RCM Private Markets Fund), and Woodline Partners, among others.
Image Source: Skyryse
The pitch is bold and deceptively simple. Skyryse is building a “universal operating system for flight,” SkyOS, designed to replace the cockpit’s maze of mechanical controls with a computer-driven system that makes routine flight easier and emergency situations more manageable. The bigger claim is standardization: if you can make the interface and controls feel consistent across aircraft, you reduce training friction, lower pilot workload, and create fewer opportunities for human error when the stakes spike.
The real work starts after the press release
Skyryse says the funding will be used to accelerate FAA certification and scale SkyOS across additional aircraft platforms, including the Black Hawk. That is the hard part, and also the part most startups never reach. Aviation is where software has to prove itself in edge cases, repeatedly, with zero tolerance for surprises, because “mostly works” is another way of saying “eventually fails.”
The bet hiding inside the headlines
If Skyryse clears certification and can port SkyOS across aircraft types the way software ports across devices, it could unlock a new category of safety automation for fleets that cannot afford downtime, confusion, or long training cycles. Emergency response, defense modernization, and industrial aviation are all markets where reliability is the product, and simplicity is the differentiator. In a world obsessed with shipping faster, Skyryse is playing a different game: getting permission to ship at all.
Keep scrolling for the latest LA venture rounds, fund news and acquisitions.
🤝 Venture Deals
LA Companies
- Accrual announced it has raised $75M in new funding led by General Catalyst, with participation from Go Global Ventures, Pruven Capital, Edward Jones Ventures, and a group of founders and industry executives. The company says the raise supports its official launch and continued buildout, alongside early partner firms, investors, and advisors. - learn more
- Morpheus Space secured a $15M strategic investment led by Alpine Space Ventures and the European Investment Fund, with continued support from existing investors, to fuel its next phase of growth. The company says it will use the capital to expand mass-production capacity and its team at its Dresden “Reloaded” facility, helping industrialize its GO-2 electric propulsion systems and meet rising demand from large satellite constellations. - learn more
- Machina Labs raised a $124M Series C to build its first large-scale “Intelligent Factory,” a U.S.-based production site aimed at rapidly manufacturing complex metal structures for defense, aerospace, and advanced mobility. The company says the funding, backed by investors including Woven Capital, Lockheed Martin Ventures, Balerion Space Ventures, and Strategic Development Fund, will help it scale its AI-and-robotics “software-defined” manufacturing approach from breakthrough tech into high-throughput production infrastructure. - learn more
- Midi Health raised a $100M Series D led by Goodwater Capital, with new investors Foresite Capital and Serena Ventures joining and existing backers including GV, Emerson Collective, and others returning, valuing the company at over $1B. The women’s telehealth provider says it will use the funding to scale beyond menopause care into a broader, AI-enabled women’s health platform, expanding access and using AI to personalize care and streamline clinical operations. - learn more
- Mitra EV raised $27M in financing, combining equity led by Ultra Capital with a credit facility from S2G Investments, to expand its “no upfront capital” fleet electrification model. The Los Angeles-based company says it will use the money to grow its shared charging network, roll out additional fleet solutions, and expand into new markets, positioning itself as a fully managed package that bundles EV leasing, overnight charging, and access to shared fast-charging hubs. - learn more
- Plug raised a $20M Series A to scale its EV-first marketplace, following $60M in used EV sales since launching in 2024. The round was led by Lightspeed with participation from Galvanize and existing investors including Autotech Ventures, Leap Forward Ventures, and Renn Global, as Plug positions itself as infrastructure for the coming wave of off-lease EV inventory with EV-native pricing, battery health insights, and faster dealer transactions. - learn more
- Breezy, a Los Angeles-based AI operating system for residential real estate professionals, raised an oversubscribed $10M pre-seed round led by Ribbit Capital, with participation from Fifth Wall, DST Global, Liquid 2 Ventures, O.G. Venture Partners, and others. The company says it will use the funding to strengthen its product and data platform, grow engineering and design, invest in security, and prepare for broader U.S. and international rollout. - learn more
LA Venture Funds
- Upfront Ventures participated in Daytona’s $24M Series A, a round led by FirstMark Capital with participation from Pace Capital and existing investors E2VC and Darkmode, plus strategic checks from Datadog and Figma Ventures. Daytona is building “composable computers” for AI agents, essentially programmatic, stateful sandboxes that can be spun up, paused, and snapshotted on demand so agents can safely run code and explore many paths in parallel at scale. - learn more
- Second Sight Ventures participated in Willie’s Remedy+’s $15M Series A, a round led by Left Lane Capital to fuel national retail expansion and continued product development for its hemp-derived THC beverages positioned as an alcohol alternative. The company says it has already sold 400,000+ bottles in under a year and claims the top spot for online THC beverage sales as it gears up for broader distribution in 2026. - learn more
- Navitas Capital led Cadastral’s $9.5M funding round, with participation from JLL Spark Global Ventures, AvalonBay, Equity Residential, and 1Sharpe. Cadastral says it will use the capital to accelerate product development and expand go-to-market for its vertical AI platform, positioning the product as an “AI analyst in a box” that automates core commercial real estate workflows like underwriting and due diligence. - learn more
- B Capital participated in Lunar Energy’s $232M raise, which the company disclosed as two rounds: a $102M Series D led by B Capital and Prelude Ventures, and a previously unannounced $130M Series C led by Activate Capital. The startup says it will use the capital to rapidly scale home-battery manufacturing and deployments, turning those distributed systems into a grid-supporting virtual power plant as electricity demand surges. - learn more
- B Capital participated in Goodfire’s $150M Series B at a $1.25B valuation, a round that also included investors like Juniper Ventures, DFJ Growth, Salesforce Ventures, Menlo Ventures, Lightspeed, South Park Commons, Wing, and Eric Schmidt. Goodfire says it will use the funding to scale its interpretability-driven “model design environment,” aimed at helping teams understand, debug, and deliberately shape how AI models behave in high-stakes settings. - learn more
- Helena participated in Positron AI’s oversubscribed $230M Series B at a post-money valuation above $1B, alongside strategic investors including Qatar Investment Authority and Arm. The round was co-led by ARENA Private Wealth, Jump Trading, and Unless, and the company says it will use the capital to scale energy-efficient AI inference now and accelerate its next-generation “Asimov” silicon roadmap. - learn more
- Smash Capital participated in ElevenLabs’ $500M Series D, which values the company at $11B as it scales its voice and conversational AI products for enterprise use. The round was led by Sequoia Capital with support from existing backers like Andreessen Horowitz and ICONIQ Capital, plus additional participation including Lightspeed Venture Partners. - learn more
- MTech Capital participated in Pasito’s $21M Series A, a round led by Insight Partners with additional participation from Y Combinator. Pasito says it’s building an AI-native workspace for group health, life, and retirement benefits that turns messy, unstructured plan and census data into a unified layer so carriers and brokers can automate workflows end-to-end, from quoting and enrollment to support and claims. - learn more
- Rebel Fund participated in Ruvo’s $4.6M seed round, led by 1confirmation with participation from Coinbase Ventures and others, as the Y Combinator-backed fintech expands its cross-border payments infrastructure between Brazil and the U.S. Ruvo says it operates like a U.S. dollar account for Brazilians, combining Pix, stablecoins, ACH/wire transfers, and a Visa card in one app to speed up remittances by reducing intermediaries. - learn more
- Rainfall Ventures participated in a seed funding round for Deft Robotics alongside Spring Camp, backing the company’s push to build AI-driven automation tools for manufacturers. The round amount wasn’t disclosed in the announcement, but the funding is positioned to help Deft scale product development and customer deployments in industrial settings. - learn more
- Trousdale Ventures participated in CesiumAstro’s Series C by leading the $270M equity portion of a $470M total growth-capital raise, alongside investors including Woven Capital, Janus Henderson Investors, and Airbus Ventures. CesiumAstro says the broader financing also includes $200M from Export-Import Bank of the United States and J.P. Morgan, and will fund a major U.S. scale-up including a new 270,000-square-foot HQ and expanded manufacturing to accelerate deployment of its software-defined, AI-enabled space communications platforms. - learn more
- Mucker Capital participated in Linq’s $20M Series A, which was led by TQ Ventures to help the company become infrastructure for AI assistants that run directly inside messaging apps. Linq’s platform lets developers and businesses deploy assistants through channels like iMessage, RCS, and SMS, and the company says the funding will go toward expanding the team, building a go-to-market motion, and continuing to develop the product. - learn more
- Sound Ventures participated in Day AI’s $20M Series A, which was led by Sequoia Capital with additional participation from Greenoaks, Conviction, and Permanent Capital. Day AI says the funding will help scale its AI-native CRM platform and support its move into general availability, positioning “CRMx” as a faster, context-driven alternative to legacy systems that turn simple questions into slow projects. - learn more
- Chaac Ventures participated in Arbor’s $6.3M seed round, which was led by 645 Ventures with additional backing from Next Play Ventures, Comma Capital, and angel investors. Arbor is building an AI interview and research platform that captures frontline employee and customer conversations and turns that qualitative “ground truth” into structured operational intelligence leaders can act on quickly, without slow surveys or pricey consultants. - learn more
- B Capital participated in When’s $10.2M Series A, a round co-led by ManchesterStory and 7wire, with new investor Mairs & Power Venture Capital and returning backers Enfield Capital Partners, TTV Capital, and Alumni Ventures. When says it helps employers and departing or transitioning employees navigate health coverage changes by steering people to more affordable alternatives to COBRA through an AI-powered marketplace and targeted reimbursements, with the new capital going toward team growth and expanding into more transition scenarios like Medicare eligibility and early retirements. - learn more
