West LA-Based Biotech ImmixBio - Maker of Cancer Treatments - Files for an IPO

Keerthi Vedantam

Keerthi Vedantam is a bioscience reporter at dot.LA. She cut her teeth covering everything from cloud computing to 5G in San Francisco and Seattle. Before she covered tech, Keerthi reported on tribal lands and congressional policy in Washington, D.C. Connect with her on Twitter, Clubhouse (@keerthivedantam) or Signal at 408-470-0776.

West LA-Based Biotech ImmixBio - Maker of Cancer Treatments - Files for an IPO

ImmixBio, a West L.A.-based startup developing cancer therapies, announced on Friday it submitted a confidential filing to go public.

Ilya Rachman, chief executive of the nine-year-old company which has developed a combination therapy meant to prevent cancers from resisting treatments and evolving, would not specify how many shares will be offered or the price range.


ImmixBio CEO Dr. Ilya Rachman/ Courtesy of ImmixBio

The company's therapy has shown promising results in treating glioblastoma, ovarian tumors and multiple myeloma in preclinical studies

Rachman said he wants to take the company public so he can further the development of the cancer drug and expand it to treat colon cancer. He also hopes to continue Immix's work on inflammatory bowel disease treatment that is in preclinical stages.

"This company truly benefits the ultimate consumer, which is the massive patient population, as well as investors who want to back worthwhile clinical innovation that bring meaningful improvement to standards of care in oncology," said Rachman.

The therapy is currently undergoing clinical trials to treat ovarian cancer, breast cancer, pancreatic cancer and solid tumors to determine what dose is appropriate for patients. The first U.S. patient was dosed in 2020.

Early clinical trials showed promising results for patients dealing with soft-tissue sarcoma, a rare type of cancer. Using Immix therapy, patients' cancers were controlled for roughly four months, which allows doctors to continue experimenting with different treatments before the cancer either grows or evolves.

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Personality Assessments Improving Workplace Dynamics

Misunderstandings can have significant and sometimes severe impacts, far beyond the hilarious cake pictured above. Many organizations are increasingly using personality assessments to improve team dynamics and productivity. Tests like the Enneagram, Myers-Briggs Type Indicator (MBTI), and DISC assessment are valuable tools for developing existing teams in addition to hiring new employees. These assessments provide insights into team members' motivations, communication styles, and work preferences, helping colleagues understand each other better. By highlighting the different personalities within a team, these tests can enhance communication, resolve conflicts, and optimize task assignments based on individual strengths. As companies aim for greater efficiency and collaboration, the Enneagram, MBTI, and DISC assessments are becoming essential for transforming established teams into more effective and cohesive units.


Image Source: iEQ9

Enneagram

The Enneagram test is a sophisticated personality assessment that categorizes individuals into nine distinct personality types, each defined by unique motivations, fears,and behavioral patterns. This holistic approach enhances team dynamics in a business setting by fostering self-awareness, improving communication, and facilitating conflict resolution among team members. By understanding different personality types, teams can optimize their composition, tailor professional development, and create a more empathetic and collaborative environment. This framework not only helps leaders adapt their styles to better support diverse team members but also promotes inclusivity and effective collaboration, ultimately leading to improved team performance, productivity, and retention.

Resources:iEQ9. We recommend getting an Enneagram coach to get the most out of the results.

Key Features: Focus on core motivations. Accounts for personality shifts under stress or growth. Offers practical, actionable guidance for personal growth. Uses a dynamic, adaptive questioning approach. Claims 95% accuracy rate through advanced techniques.


Image Source: DiSC Profile

DiSC (Dominance, Influence, Steadiness, and Conscientiousness)

The DiSC assessment is a widely used behavioral analysis tool that categorizes individuals into four primary personality types: Dominance, Influence, Steadiness, and Conscientiousness. For businesses, DiSC provides valuable insights into employees' communication styles, work preferences, and motivations. By understanding these behavioral tendencies, teams can improve collaboration, reduce conflicts, and enhance overall productivity. Implementing DiSC in a business setting can lead to more effective leadership, tailored communication strategies, and optimized task allocation based on individual strengths.

Resources:DiSC Profile.

Key Features: Designed specifically for workplace applications. Focuses on observable behaviors rather than psychological traits. Widely researched and validated over 40+ years. Provides practical strategies for improving interactions.


Image Source: The Myers-Briggs Company

The Myers-Briggs Type Indicator (MBTI)

The Myers-Briggs Type Indicator (MBTI) is a widely used personality assessment tool that categorizes individuals into 16 distinct personality types based on four dichotomies: Extraversion/Introversion, Sensing/Intuition, Thinking/Feeling, and Judging/Perceiving. For businesses, the MBTI provides valuable insights into employees' communication styles, decision-making processes, and work preferences.This helps promote a more productive workplace, and enables employees to become involved in more meaningful ways, all while leveraging everyone’s unique strengths.

Resources:The Myers-Briggs Company.

Key Features: Focuses on preferences rather than traits. Focuses on how people perceive and judge information. Widely used in business and career counseling


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🥊📱Startups Battling Election Deepfakes and LA’s First Tech CEO Summit

🔦 Spotlight

Happy Friday Los Angeles!

YouMail, based in Irvine, and Pindrop have partnered to create the Election Communication Defense Grid (ECDG), a platform designed to combat AI-generated and deepfake calls that could interfere with US elections. This collaboration leverages YouMail's extensive sensor network, which analyzes over 20 million phone numbers monthly, and Pindrop's Pulse™ Inspect technology to detect AI-generated speech. The system actively monitors and analyzes potentially problematic political robocalls, having already examined calls from numerous Congress members and political candidates in 2024. When AI-generated calls are identified, YouMail Protective Services swiftly notifies carriers and enforcement agencies to shut down these campaigns, minimizing potential harm. This partnership represents a significant step forward in protecting the public from malicious communication tactics during critical election periods.


✨ Featured Event ✨

LA TECH CEO SUMMIT

WHEN: Thursday, September 26 -- Friday, September 27, 2024

LOCATION: Terranea Resort: 100 Terranea Way, Rancho Palos Verdes, CA 90275

LA’s tech leadership is set to reunite after a long break! Join us for the highly anticipated LA Tech CEO Summit, taking place September 26-27 at the stunning Terranea Resort. This exclusive event offers a unique chance to connect with top tech founders and CEOs, including industry key figures like Adam Miller (Founding CEO of Cornerstone), Ian Siegel (CEO of ZipRecruiter), Shivani Siroya (CEO of Tala), Eddy Lu (CEO of GOAT), and other influential leaders. This two day summit will focus on building strong connections, sharing insights, and fortifying the local tech community. Don’t miss this opportunity to engage with the best minds in LA tech!

Learn More Here

Register Here


🤝 Venture Deals

LA Companies

  • Starpath, a developer of robotic propellant production factories raised a $12M Seed Round co-led by 8VC and Fusion Fund, and joined by Day One Ventures, Balerion Space, and Indicator Ventures. - learn more

LA Venture Funds

  • Anthos Capital led a $4M Funding Round for Mudstack, a startup whose software helps game developers organize and share game assets like graphics and code. - learn more

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🎓 LA’s Startup Edge Round 2

In light of last week’s article, we want to highlight some additional schools that have a significant impact on LA’s tech landscape. If we’ve missed any schools or founders worth including let us know!


Image Source: LMU

Loyola Marymount University

LMU plays a significant role in developing Los Angeles' tech workforce by offering various programs and resources for aspiring entrepreneurs and innovators. The university fosters innovation and entrepreneurship through:

  • LMU College of Business Administration: Provides entrepreneurship-focused programs and courses, including the Entrepreneurship Program, which offers hands-on experience and mentorship opportunities for students interested in starting their own businesses.
  • Frank R. Seaver College of Science and Engineering: Collaborates with industry partners on research projects and offers programs like the Engineering Clinic, where students work on real-world problems for corporate sponsors.
  • Fred Kiesner Center for Entrepreneurship: Serves as a hub for entrepreneurial activities, offering resources such as the Business Incubator program, pitch competitions, and networking events to support student and faculty startups.

Companies Founded by LMU Alumni: Liquid I.V. by Brandin Cohen, Dave by Jason Wilk, Abstract by Pat Utz


Image Source: CSULB

California State University, Long Beach (CSULB)

CSULB plays a significant role in developing Long Beach's entrepreneurial ecosystem through various programs and resources. The Institute for Innovation & Entrepreneurship (IIE) at CSULB serves as a central hub, offering initiatives like monthly Innovation Hours, a social justice entrepreneurship program, and the annual Sunstone Innovation Challenge with $50,000 in prizes. CSULB fosters innovation and entrepreneurship through:

Companies Founded by CSULB Alumni: Oculus VR and Anduril by Palmer Luckey (technically not an alumni because he dropped out before graduating), Dreamworks Animation by Steven Spielberg


Image Source: Claremont McKenna College

The Claremont Colleges

The Claremont Colleges serve as a significant source of talent for Los Angeles' tech and venture capital workforce, leveraging their strong academic programs and entrepreneurial resources. Harvey Mudd College, renowned for its exceptional engineering program, contributes a substantial number of highly skilled graduates to the tech sector. The consortium's collaborative approach to fostering innovation is exemplified by initiatives like:

  • The HIVE: This hub enhances students' creative problem-solving skills through collaborative and interdisciplinary experiences.
  • Claremont McKenna College's Silicon Valley Program: Offers students an immersive off-campus study experience that integrates internships, coursework, and networking opportunities in the heart of the tech industry, preparing them for careers in innovation and venture capital..
  • The Makerspace at Harvey Mudd College: An 8,000 SF student-run facility that allows students to prototype and develop innovative ideas, fostering a hands-on approach.

Companies Founded by Claremont Alumni: TechCrunch by Michael Arrington (CMC), KKR by Henry Kravis (CMC) & George Roberts (CMC), Sun Basket by Adam Zbar (Pomona), GitHub by Tom Preston-Werner (technically not an alumni because he dropped out before graduating from Harvey Mudd)


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