Quantum Is Coming: Caltech and Amazon’s New Computing Site is Open

Keerthi Vedantam

Keerthi Vedantam is a bioscience reporter at dot.LA. She cut her teeth covering everything from cloud computing to 5G in San Francisco and Seattle. Before she covered tech, Keerthi reported on tribal lands and congressional policy in Washington, D.C. Connect with her on Twitter, Clubhouse (@keerthivedantam) or Signal at 408-470-0776.

Caltech and Amazon’s New Computing Site

In 2019, Caltech announced a partnership with Amazon Web Services to resurrect a 21,000-square-foot building as a shrine to quantum computing. Inside, researchers from MIT, Stanford, Harvard and more are planning to build out quantum computers that may look more like the giant IBM computers from the 50s than our current laptops.

Now, the building has officially opened.


Simply put (without getting into Scrodinger's cat), quantum computing has the ability to take a problem with several variables, generate millions of permutations or outcomes and pick the best or most efficient one.

This kind of technology has the power to transform industries that need to take a lot of risk into account. For instance, it could help pharmaceutical companies create more effective drugs without having to experiment as much. It could help doctors deliver personalized medicine by leveraging the human genome sequence. It could also help the financial sector sift through data projections of different companies to understand the risk of an investment or an acquisition. It could help delivery companies find the most efficient route in a matter of minutes.

Fernando Brand\u00e3o

Fernando Brandão, a professor of theoretical physics

The systems that power cell phones and laptops don't have the ability to process large, complex problems that could sift through millions of permutations to calculate the best solutions.

In a landmark study for quantum computing in 2019, Google said it was able to feed a problem through a quantum computer and get results in minutes. That same problem would have taken a normal computer 10,000 years to complete.

The Caltech building is one of many quantum computing projects in Amazon's portfolio. The company previously unveiled a cloud-based quantum computer called Amazon Bracket to rival Azure's quantum offering in the never ending cloud wars between the two companies.

We sat down with Fernando Brandão, a professor of theoretical physics who is co-leading the AWS Center for Quantum Computing.

How did this partnership between AWS and Caltech come about?

A lot of computing probably started 40 years ago. It was actually Caltech's Richard Feynman, who was a professor here back then, that had this idea that, on a fundamental level, nature is quantum mechanical. We need to build our computers out of something right out of quantum mechanical systems then actually quantum mechanics has some pretty different problems from the physics we learn at school, and therefore, there is an opportunity for building a better kind of computer using quantum mechanics. For 40 years, he had been developing this idea, and Caltech had played a major role.

But if you really move to the next step and scale up the technology and build a quantum computer at a scale that can be useful for society and for people, then you need very serious engineering effort and special investments; this is not something cheap to do. We need a big player, either in government or industry, to do that. Caltech can bring all the scientific expertise. And Amazon can bring other expertise in engineering and all the investment necessary to really go to the next step.

What is quantum computing?

You want to make a company that has to optimize the routes to deliver some product to a customer. What is the best route to deliver this product? This question is challenging because there are so many different possibilities. So quantum computation is exploring all of the options at the same time.

But it is not like parallel computing. There's a second step where you have to find a clever way to make the solution interfere in a way that only gives you one of the options. So Quantum computation will not speed up every problem. There are particular problems for which it gives an advantage. So the problem has to have the right structure. And a lot of the research in quantum computing is to find out which problems have the right structure so we can explore them to give better quantum solutions.

What sectors will have the first or most immediate impact of quantum computing?

This goes back to the vision of Richard Feynman from 40 years ago, where he said, "Look, let's actually build this quantum computer for nothing else than just simulating very complicated quantum mechanical systems."

I've seen industries where the bottleneck to making progress is to simulate very large quantum mechanical systems. For example, we know in pharmaceuticals we want to understand the quantum structure of molecules to make new drugs. But it's very easy to get complicated molecules [that are] out of reach for the computers that we have today.

In material science for people who are looking at batteries, for example, we have to model how these batteries work on a quantum level, and it can get very complicated, very quickly. So it would be a lot of R&D research for companies that work in energy or in pharmaceuticals or in chemistry. I think they would find quantum computation very useful.

Then at some point if you had even better machines, faster machines, bigger machines, you might end up in applications for optimization problems for logistics, currency, finance.The issue there is quantum can give an advantage, but it is a small advantage than for these simulation problems like pharmaceuticals or material science. So you need a more sophisticated machine to get there.

What are some of the bottlenecks here? What's preventing us from building this quantum computer and deploying it for pharmaceutical companies everywhere within the next year?

In a quantum mechanical system, they are very fragile, unlike the systems that we experience in our everyday life. So there is a rule of quantum mechanics that whenever you go and see how the system is, you've disturbed the system.

So what this means is that all kinds of information like the magnetic field of the environment or the temperature of some particles in the environment all affect your quantum system, so it's very hard to isolate your quantum system from these detrimental effects of the environment. And that's the challenge of quantum computers. If you don't isolate them, then there is noise in our quantum computer and this noise will spoil our operations.

At the same time we want one qubit [a unit of information in quantum computers] to interact very strongly with the other qubit to do the operation.

So you have two conflicting requirements. You want to completely isolate your qubits in the quantum computer from the environment, and that's very hard for quantum mechanical systems. But at the same time, you want [the qubits] to couple very strongly. So making these two things happen at the same time and at the scale that we need for a large number of qubits, we think that's possible. We don't see any roadblock, but it's just that it is very ambitious scientific engineering.

Where will quantum computing be in, let's say, 10 years?

I'm hoping within the next decade or so, we start getting to this stage of quantum computers where they start impacting society in a meaningful way. It's an ambitious goal, but I think we are well-positioned. So by the end of the decade, we may start having quantum machines that can solve problems of society that cannot be solved on our current computers.

This interview has been edited for clarity and brevity.

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The LA Startup Taking on One of Parenting’s Most Frustrating Problems

🔦 Spotlight

Hello Los Angeles,

Every parent knows the feeling of becoming an overnight expert in something they never wanted to learn.

For families navigating developmental delays, behavioral health needs, autism, speech therapy, occupational therapy or pediatric mental health support, that learning curve can become a full-time job. Finding the right specialist is hard enough. Getting those specialists, pediatricians, insurers and families to actually coordinate with each other? That’s often where the system breaks.

That’s the problem Los Angeles-based Village is trying to solve.

The specialty pediatrics startup raised $9.5 million in seed funding this week, led by Upfront Ventures, with participation from Bling Capital, GTMFund and Perceptive Ventures.

Its AI-powered platform is designed to bring families, providers, pediatricians and payers into one coordinated care system for children with developmental, behavioral and mental health needs.

The company was born out of co-founder Brandon Terry’s personal experience navigating care for his daughter after she was diagnosed with a rare genetic condition. Like many parents, his family faced long waitlists, high out-of-pocket costs and a fragmented web of specialists who were not necessarily working from the same playbook.

The pitch is not simply “find a provider faster.” Village wants to coordinate the entire team around a child, including occupational therapists, speech-language pathologists, behavioral therapists and pediatricians. Its AI agent, Vera, is designed to help with the administrative drag that often slows pediatric practices down: scheduling, documentation, billing and care coordination.

The company’s raise also points to a less flashy, but deeply consequential corner of health tech: making complex care easier to navigate. In specialty pediatrics, the pain point is not always the quality of care itself. It is the space between appointments, referrals, insurance approvals and provider communication where families are often left to connect the dots themselves.

So far, Village says it has built a network of more than 400 independent pediatric specialty providers in Southern California and has contracts with major commercial insurers including Blue Cross & Blue Shield, Cigna and UnitedHealthcare. The new funding will help the company expand across Southern California, into other parts of California and eventually into new states.

In other words, the next wave of healthcare infrastructure may not look like one giant hospital system. It may look more like a connected network built around the people who have been holding the system together all along: families.

And yes, in this case, it really does take a Village.

Venture deals follow below.👇


🤝 Venture Deals

    LA Companies

    • MOSH, the brain health nutrition brand co-founded by Maria Shriver and Patrick Schwarzenegger, raised a $13M Series A led by Main Street Advisors to expand nationally across grocery retailers and accelerate product innovation. The Los Angeles-based company plans to use the funding to grow its retail footprint, including an upcoming Target launch, while expanding its lineup of brain-focused nutrition products with new high-protein bars designed to support both cognitive and physical performance. - learn more
    • Spring Labs raised $5M to expand its AI-native compliance platform for banks and fintechs, with the funding led by BankTech Ventures and Haymaker Ventures. The Marina del Rey-based company is building AI agents that automate complaint handling, dispute resolution, and other compliance workflows, helping regulated financial institutions scale operations more efficiently while maintaining oversight and auditability. - learn more
    • FlowPrompt.ai secured a strategic seed investment from ART Fund SP, part of ChainBLX SPC, as the company expands its AI orchestration platform designed to help developers build and manage complex AI workflows through a visual interface. Alongside the investment, the companies also launched a global AI hackathon and builder program that will give selected founders access to funding opportunities, platform tools, and a live investor pitch event in Los Angeles later this summer. - learn more
    • Chance Studios raised $3.2M to build a unified platform for trading card game collectors, aiming to bring inventory management, marketplace activity, and community features into a single ecosystem. The round was co-led by Makers Fund and Hashed, with participation from Arbitrum Gaming Ventures, GAM3GIRL VC, and others, as the company looks to modernize how collectors buy, track, and interact around physical and digital TCG assets. - learn more

    LA Venture Funds
    • Rebel Fund participated in Moritz’s $9M seed round, backing the AI-native law firm as it looks to automate large portions of routine corporate legal work. The company combines software with experienced attorneys to speed up contract drafting and review, and says it has already handled more than $2 billion worth of contracts across over 100 companies since launching earlier this year. - learn more
    • Rebel Fund participated in Corvera’s $4.2M seed round, backing the AI-native supply chain platform as it automates back-office operations for consumer packaged goods brands. The Y Combinator-backed startup is building AI agents that can handle workflows like order processing, invoicing, and demand planning across fragmented enterprise systems, helping brands scale operations without significantly increasing headcount. - learn more
    • Chaac Ventures participated in Astrocade’s $5.6M funding round, backing the gaming startup as it builds a social gaming platform centered around community-created interactive experiences. The company is focused on blending gaming, streaming, and creator tools into a more collaborative entertainment platform, and plans to use the funding to expand development and grow its creator ecosystem. - learn more
    • Fusion VC participated in MSICS Pharma’s $3.6M funding round, backing the biotech company as it advances psilocybin-based treatments for PTSD, depression, and OCD. The company is developing medical-grade psychedelic compounds and plans to use the funding to expand production, accelerate clinical trials, and prepare for broader commercialization as interest in psychedelic therapies continues to grow. - learn more
    • JAM Fund participated in Fun’s $72M Series A, backing the payments infrastructure startup as it scales its platform for moving money across fintech and digital asset applications. The round was co-led by Multicoin Capital and SignalFire, and the company plans to use the funding to expand internationally, pursue acquisitions, and deepen its infrastructure stack as demand grows for faster global payment systems. - learn more

    LA Exits

    • Tapin2 was acquired by Greater Sum Ventures, joining MyVenue as part of GSV’s expanded point-of-sale technology platform for stadiums, arenas and live entertainment venues. Tapin2 provides self-service, suite catering and mobile ordering technology for high-volume sports and entertainment venues, while MyVenue offers cloud-native POS software across concessions, premium seating, retail, in-seat ordering and other venue operations. Together, the companies say their technology is used in more than 70% of MLB and NFL stadiums. Terms of the transaction were not disclosed. - learn more
    • Motiv Space Systems signed a definitive agreement to be acquired by Rocket Lab, bringing its space robotics, motion control systems and precision spacecraft mechanisms into Rocket Lab’s growing space systems business. Motiv’s technology has supported major missions including NASA’s Mars Perseverance rover and lunar rover programs, and the company will be rebranded as Rocket Lab Robotics after the deal closes, which is expected in the second quarter of 2026. - learn more
    • Robyn was acquired by Los Angeles-based Tot Squad, bringing its AI-powered doula tool into Tot Squad’s broader support platform for expecting and new moms. Robyn’s AI was trained on more than 70,000 de-identified messages between parents and doulas, and the acquisition will help Tot Squad offer free, around-the-clock pregnancy and early motherhood guidance alongside access to human experts like doulas, lactation consultants and sleep coaches. Terms of the deal were not disclosed. - learn more

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      Match Goes Niche With $100M Move

      🔦 Spotlight

      Hello Los Angeles,

      It’s May, and LA is about to have one of its more important weeks.

      The Milken Institute Global Conference 2026 returns to Beverly Hills next week, bringing together thousands of investors, operators, policymakers, and executives. It’s one of the few places where public markets, private capital, and tech actually overlap in the same rooms, and where you can usually get an early read on what capital is leaning into before it fully shows up in the data.

      This year, one theme is already starting to surface. Platforms are getting more specific, not more broad.

      This week’s news is a good example.

      Match Group is investing $100 million into Sniffies, a fast-growing, location-based platform built for gay, bi, trans, and queer men. It’s a notable move for a company best known for mainstream dating apps like Tinder and Hinge, and it signals a deeper push into more niche, community-driven platforms.

      Sniffies operates very differently from traditional dating apps. It’s more real-time, more map-based, and more focused on immediacy than long-term matching. In other words, it’s built around behavior, not profiles.

      And that’s what makes the investment interesting.

      For years, the dominant strategy in consumer platforms was scale, build one product that works for everyone. But what we’re seeing now is the opposite. The platforms that are gaining traction tend to be the ones that understand a specific audience deeply and build for how that group actually behaves.

      Match leaning into that shift isn’t just about expanding its portfolio. It’s a recognition that growth is coming from focus.

      And in a city like Los Angeles, that’s usually where things start.

      Below are this week’s venture deals and fund announcements across LA 👇


      🤝 Venture Deals

        LA Companies

        • Illuminant Surgical raised an $8.4M seed round to accelerate the rollout of its real-time anatomical projection platform, which aims to give surgeons enhanced visibility during procedures. The company’s “Skylight” system is designed to project internal imaging directly onto the patient, improving precision and reducing risk, and the funding will support product development and early commercialization efforts. - learn more
        • Jupid raised $840K in early funding to support its AI-native accounting platform, which is designed to automate bookkeeping, tax filing, and compliance for small businesses directly within banking platforms. The company is building what it describes as an embedded “AI accountant” that integrates with financial institutions to streamline operations for entrepreneurs, and plans to use the funding to expand partnerships and accelerate product development as demand grows for automated financial tools. - learn more
        • Lumicup raised a $4.38M Series A to expand its product line and scale manufacturing as it looks to meet growing demand for its consumer health and wellness products. The company plans to use the funding to increase production capacity, invest in new product development, and strengthen its distribution as it continues to grow its footprint in the market. - learn more
        • Counterpart raised a $50M Series C to expand its AI-driven “agentic insurance” platform, which helps small businesses manage growing legal and employment risks tied to AI adoption. The round was led by Valor Equity Partners with participation from existing investor Vy Capital, bringing the company’s total funding to $106M, and the capital will be used to launch new insurance products, expand risk management capabilities, and scale its underwriting platform. - learn more
        • Nervonik raised a $52.5M Series B to advance its next-generation peripheral nerve stimulation technology, which aims to deliver more precise, personalized treatment for chronic pain. The round was led by Amzak Health with participation from Elevage Medical Technologies, U.S. Venture Partners, Lumira Ventures, Foothill Ventures, and Shangbay Capital, and the company plans to use the funding to accelerate clinical programs and move toward commercialization. - learn more
        • LighthouseAI raised an $8M Series A to expand its AI-powered platform that helps pharmaceutical companies manage state licensing and regulatory compliance. The round was led by Boxcars Ventures with participation from TGVP and existing investors, and the company plans to use the funding to enhance product development, improve service delivery, and support continued growth as it scales across the pharma supply chain. - learn more

        LA Venture Funds
        • MANTIS Venture Capital participated in Rogo’s $75M Series C, backing the AI platform as it builds autonomous financial agents designed to streamline complex workflows for banks and investment firms. The round was led by Sequoia Capital and included a mix of major financial institutions and venture firms, signaling strong demand for AI tools that can augment decision-making across high-stakes finance. - learn more
        • M13 participated in Chord’s $7M funding round, backing the AI commerce platform as it builds a “context layer” designed to unify fragmented data, tools, and workflows for retail brands. The round was led by Equal Ventures with participation from Chingona Ventures and CEAS Investments, and the company aims to help operators move beyond dashboards toward systems that can make real-time decisions and automate actions across the business. - learn more
        • Fika Ventures participated in Lumian’s funding round, backing the startup as it launches an AI-native Amazon agency designed to automate and optimize how brands operate on the marketplace. The company is focused on replacing traditional agency workflows with AI-driven systems that can manage everything from advertising to operations in real time, reflecting a broader shift toward automation in e-commerce. - learn more
        • Riot Ventures co-led True Anomaly’s $650M Series D, backing the defense space startup as it scales spacecraft, software, and autonomous systems designed for national security missions in orbit. The round values the company at around $2.2 billion and brings total funding to over $1 billion since its 2022 founding, and the company plans to use the capital to accelerate mission deployments, expand manufacturing, and grow its workforce as demand increases for space-based defense capabilities. - learn more
        • Clocktower Technology Ventures participated in Clarasight’s $11.5M Series A, backing the AI-powered travel and expense platform as it works to unify fragmented enterprise data into a single system. The round was led by AlleyCorp with participation from several travel and fintech-focused investors, and the company plans to use the funding to expand product development and scale go-to-market efforts as demand grows for AI-driven efficiency in corporate travel. - learn more
        • Halogen Ventures and Mucker Capital participated in SkyfireAI’s $11M seed round, backing the startup as it builds an AI-native platform for coordinating autonomous, multi-drone operations. The company’s software is designed for public safety and defense use cases, helping teams deploy and manage fleets of drones with greater speed and efficiency without increasing staffing, and it plans to use the funding to accelerate product development, expand its team, and scale deployments with government and mission-critical customers as demand grows for autonomous drone systems. - learn more
        • Matter Venture Partners led OpenLight’s $50M Series A-1, with participation from Acclimate Ventures, Catapult Ventures, and existing investors, backing the photonics company as it scales its next-generation chip platform for AI infrastructure. The funding brings total capital raised to $84M and will be used to accelerate global deployment of its silicon photonics technology across data centers, telecom, and other high-bandwidth applications. - learn more
        • Alexandria Venture Investments participated in Fathom Therapeutics’ $47M Series A, backing the biotech startup as it applies quantum chemistry and AI to design next-generation small molecule drugs. The oversubscribed round was led by Sutter Hill Ventures with participation from Chemistry and other investors, and the company plans to advance its platform, which simulates protein behavior inside living cells to accelerate drug discovery. - learn more

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          Netflix Doubles Down on LA

          🔦 Spotlight

          Hey Los Angeles.

          Goodbye Coachella, hello Stagecoach. The desert doesn’t stay quiet for long, and neither does LA’s entertainment machine.

          This week, that momentum showed up in a more permanent way.

          Netflix is expanding its footprint in Los Angeles with a major move to take over and invest in Radford Studio Center, a historic production lot in Studio City. The company is planning a long-term transformation of the site, with upgrades to soundstages, production offices, and infrastructure designed to support the next generation of film and television production.

          It’s a notable shift in a moment when production has been under pressure in California, with studios increasingly looking outside the state for cost advantages. Netflix going deeper in LA, and specifically into a legacy studio lot, signals a different kind of commitment. Not just to content, but to where that content actually gets made.

          And it comes at a time when the streaming wars have matured. Growth is harder, budgets are tighter, and the focus has shifted from scale at all costs to efficiency and control. Owning or operating more of the production environment gives Netflix tighter control over timelines, costs, and output.

          For Los Angeles, it’s a reminder of what still anchors the city. Even as AI, defense tech, and infrastructure startups continue to rise, entertainment remains one of the few industries where LA isn’t just competitive, it’s foundational.

          Different headlines each week, but a consistent theme underneath them. Whether it’s power, autonomy, or content, the companies that matter are investing in the layers they don’t want to outsource.

          And in this case, that layer is Hollywood itself.

          Below are this week’s venture deals, fund announcements, and acquisitions across LA 👇


          🤝 Venture Deals

            LA Venture Funds

            • UP Partners and Calm Ventures participated in Reliable Robotics’ $160M funding round, backing the autonomous aviation company as it advances pilotless flight technology for cargo and passenger aircraft. The round included a mix of new and existing investors, and the company plans to use the capital to accelerate certification efforts and expand deployment of its autonomous systems across commercial aviation. - learn more
            • Blue Heron Ventures participated in Tava Health’s $40M Series C, backing the company as it expands its tech-enabled mental health platform into a more integrated, full-stack system for providers, employers, and health plans. The round was led by Centana Growth Partners with participation from existing investors, and the company plans to use the funding to roll out new AI-powered tools and broaden access to care while reducing administrative friction across the system. - learn more
            • Vamos Ventures participated in Zócalo Health’s $15M Series A, backing the company as it scales its tech-enabled, community-based primary care model focused on high-need and underserved populations. The round was led by .406 Ventures with participation from existing and new investors, and the company plans to use the funding to expand its clinics and deepen partnerships with Medicaid programs as demand for accessible care grows. - learn more

            LA Exits
            • Studio71 has been acquired by Fixated as part of a broader deal in which German media company ProSiebenSat.1 sold its North American creator business, giving Fixated a large-scale network of creators and podcast operations and significantly expanding its footprint as it continues an aggressive roll-up strategy in the creator economy. The move signals continued consolidation in the space, with Fixated building a more vertically integrated platform across talent management, content production, and distribution. - learn more
            • Bonsai Health has been acquired by ModMed, bringing its AI-powered patient engagement platform into a broader healthcare software ecosystem. The deal is aimed at integrating Bonsai’s “agentic AI” capabilities into ModMed’s platform to automate patient outreach, fill care gaps, and improve scheduling across a network of nearly 50,000 providers. - learn more

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