Quantum Is Coming: Caltech and Amazon’s New Computing Site is Open

Keerthi Vedantam

Keerthi Vedantam is a bioscience reporter at dot.LA. She cut her teeth covering everything from cloud computing to 5G in San Francisco and Seattle. Before she covered tech, Keerthi reported on tribal lands and congressional policy in Washington, D.C. Connect with her on Twitter, Clubhouse (@keerthivedantam) or Signal at 408-470-0776.

Caltech and Amazon’s New Computing Site

In 2019, Caltech announced a partnership with Amazon Web Services to resurrect a 21,000-square-foot building as a shrine to quantum computing. Inside, researchers from MIT, Stanford, Harvard and more are planning to build out quantum computers that may look more like the giant IBM computers from the 50s than our current laptops.

Now, the building has officially opened.


Simply put (without getting into Scrodinger's cat), quantum computing has the ability to take a problem with several variables, generate millions of permutations or outcomes and pick the best or most efficient one.

This kind of technology has the power to transform industries that need to take a lot of risk into account. For instance, it could help pharmaceutical companies create more effective drugs without having to experiment as much. It could help doctors deliver personalized medicine by leveraging the human genome sequence. It could also help the financial sector sift through data projections of different companies to understand the risk of an investment or an acquisition. It could help delivery companies find the most efficient route in a matter of minutes.

Fernando Brand\u00e3o

Fernando Brandão, a professor of theoretical physics

The systems that power cell phones and laptops don't have the ability to process large, complex problems that could sift through millions of permutations to calculate the best solutions.

In a landmark study for quantum computing in 2019, Google said it was able to feed a problem through a quantum computer and get results in minutes. That same problem would have taken a normal computer 10,000 years to complete.

The Caltech building is one of many quantum computing projects in Amazon's portfolio. The company previously unveiled a cloud-based quantum computer called Amazon Bracket to rival Azure's quantum offering in the never ending cloud wars between the two companies.

We sat down with Fernando Brandão, a professor of theoretical physics who is co-leading the AWS Center for Quantum Computing.

How did this partnership between AWS and Caltech come about?

A lot of computing probably started 40 years ago. It was actually Caltech's Richard Feynman, who was a professor here back then, that had this idea that, on a fundamental level, nature is quantum mechanical. We need to build our computers out of something right out of quantum mechanical systems then actually quantum mechanics has some pretty different problems from the physics we learn at school, and therefore, there is an opportunity for building a better kind of computer using quantum mechanics. For 40 years, he had been developing this idea, and Caltech had played a major role.

But if you really move to the next step and scale up the technology and build a quantum computer at a scale that can be useful for society and for people, then you need very serious engineering effort and special investments; this is not something cheap to do. We need a big player, either in government or industry, to do that. Caltech can bring all the scientific expertise. And Amazon can bring other expertise in engineering and all the investment necessary to really go to the next step.

What is quantum computing?

You want to make a company that has to optimize the routes to deliver some product to a customer. What is the best route to deliver this product? This question is challenging because there are so many different possibilities. So quantum computation is exploring all of the options at the same time.

But it is not like parallel computing. There's a second step where you have to find a clever way to make the solution interfere in a way that only gives you one of the options. So Quantum computation will not speed up every problem. There are particular problems for which it gives an advantage. So the problem has to have the right structure. And a lot of the research in quantum computing is to find out which problems have the right structure so we can explore them to give better quantum solutions.

What sectors will have the first or most immediate impact of quantum computing?

This goes back to the vision of Richard Feynman from 40 years ago, where he said, "Look, let's actually build this quantum computer for nothing else than just simulating very complicated quantum mechanical systems."

I've seen industries where the bottleneck to making progress is to simulate very large quantum mechanical systems. For example, we know in pharmaceuticals we want to understand the quantum structure of molecules to make new drugs. But it's very easy to get complicated molecules [that are] out of reach for the computers that we have today.

In material science for people who are looking at batteries, for example, we have to model how these batteries work on a quantum level, and it can get very complicated, very quickly. So it would be a lot of R&D research for companies that work in energy or in pharmaceuticals or in chemistry. I think they would find quantum computation very useful.

Then at some point if you had even better machines, faster machines, bigger machines, you might end up in applications for optimization problems for logistics, currency, finance.The issue there is quantum can give an advantage, but it is a small advantage than for these simulation problems like pharmaceuticals or material science. So you need a more sophisticated machine to get there.

What are some of the bottlenecks here? What's preventing us from building this quantum computer and deploying it for pharmaceutical companies everywhere within the next year?

In a quantum mechanical system, they are very fragile, unlike the systems that we experience in our everyday life. So there is a rule of quantum mechanics that whenever you go and see how the system is, you've disturbed the system.

So what this means is that all kinds of information like the magnetic field of the environment or the temperature of some particles in the environment all affect your quantum system, so it's very hard to isolate your quantum system from these detrimental effects of the environment. And that's the challenge of quantum computers. If you don't isolate them, then there is noise in our quantum computer and this noise will spoil our operations.

At the same time we want one qubit [a unit of information in quantum computers] to interact very strongly with the other qubit to do the operation.

So you have two conflicting requirements. You want to completely isolate your qubits in the quantum computer from the environment, and that's very hard for quantum mechanical systems. But at the same time, you want [the qubits] to couple very strongly. So making these two things happen at the same time and at the scale that we need for a large number of qubits, we think that's possible. We don't see any roadblock, but it's just that it is very ambitious scientific engineering.

Where will quantum computing be in, let's say, 10 years?

I'm hoping within the next decade or so, we start getting to this stage of quantum computers where they start impacting society in a meaningful way. It's an ambitious goal, but I think we are well-positioned. So by the end of the decade, we may start having quantum machines that can solve problems of society that cannot be solved on our current computers.

This interview has been edited for clarity and brevity.

https://twitter.com/KeerthiVedantam
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How to Navigate LA Tech Week 2026

🔦 Spotlight

Happy Friday, Los Angeles.

Next week, hundreds of tech events will take over the city, bringing founders, investors, engineers and creators together from October 12 through 18.

Calling LA Tech Week a conference does not quite capture the experience.

Presented by Andreessen Horowitz, Tech Week is a decentralized collection of panels, workshops, demonstrations and gatherings hosted independently by startups, venture firms and technology companies. There is no convention center or central stage. The programming stretches from Santa Monica and Venice to Culver City, Downtown, El Segundo and beyond.

In other words, the city is the venue.

AI remains the dominant theme for 2026, appearing across enterprise software, healthcare, finance, media and the creator economy. The schedule also reflects industries where Los Angeles has built a particular advantage, including aerospace, defense, robotics, advanced manufacturing, entertainment and consumer technology.

That range is what makes LA Tech Week distinct. It brings together the software companies shaping what comes next with the industries that already define Southern California.

The challenge is deciding where to show up.

Our advice: apply early and organize your schedule by neighborhood. Crossing from Santa Monica to Downtown may look manageable on a calendar created by someone who has never driven in Los Angeles.

To help you spend more time meeting people and less time crossing the city, we have organized each day’s events by location:

You can also browse the complete official LA Tech Week calendar.

Plan carefully, but do not fill every minute. The best conversation of the week may be the one that was never on your calendar.

More from this week’s LA startup and venture scene below.

🤝 Venture Deals

    LA Companies

    • El Segundo-based Gallatin AI raised a $50M Series A from new and existing investors including 8VC and Silent Ventures, bringing its total funding to $70M. The defense technology startup will expand its engineering team and advance Navigator, an AI platform that helps U.S. military units coordinate vehicle readiness, supplies, medical logistics and other mission-support operations. - learn more
    • Pasadena-based quantum computing startup Oratomic raised a $475M Series B at a $5.4B valuation, just three months after its Series A. ARCH Venture Partners, Spark Capital, Khosla Ventures, Index Ventures, General Catalyst and Bezos Expeditions co-led the round, bringing Oratomic’s total funding to $775M as it works toward a commercially viable, fault-tolerant quantum computer by 2030. - learn more
    • Torrance-based Fortastra raised a $30M Series A led by First In, with participation from Upfront Ventures, Space Capital, Rsquared, Side Door Ventures, ATX Ventures and existing investors. The company will use the capital to develop its next-generation maneuverable spacecraft, expand its engineering and operations teams and scale production of systems designed to protect critical assets in orbit. - learn more
    • Parallel Systems raised a $100M Series C led by AVP, with participation from Hillspire, Agility Global, Cobalt Capital, Anthos Capital, Congruent Ventures, Riot Ventures and Collaborative Fund. Founded by former SpaceX engineers, the company will use the funding to scale production and commercial deployment of its autonomous, battery-electric Panther rail vehicles, which are designed to make short-haul freight more competitive with trucking. - learn more
    • Gaming studio Gardens Interactive secured more than $35M in a Series B led by Lightspeed, with participation from Sequoia Capital, Index Ventures, Accel, Innovation Endeavors, Zenith Capital and other investors. The company will use the funding to launch and operate its debut social role-playing “strandbox” game, an evolving multiplayer world shaped by players’ actions and interactions. - learn more
    • Outer Spaces raised an $8M pre-seed round led by Upfront Ventures, with participation from Unlock Venture Partners, Mucker Capital and Genius Ventures. The startup is developing outdoor furnishings with integrated solar panels and batteries, turning backyards into sources of clean energy and backup power. - learn more
    • Furientis raised a $25M seed round led by Benchmark at a reported $125M valuation, following a $5M pre-seed announced in May. The defense startup will use the capital to scale production of lower-cost missile interceptors designed to be assembled quickly with readily available components, with a long-term goal of producing 1,000 systems annually at each factory. - learn more
    • Hiyo raised a $20.8M Series B led by Constellation Brands, with returning investor Live Nation also participating. The nonalcoholic beverage company will use the funding to expand its adaptogen- and nootropic-infused social tonics across more than 13,000 retail locations while growing its presence at hospitality venues and live events. - learn more
    LA Venture Funds
    • Navitas Capital participated in Vesta’s $30M Series B, which was led by Conversion Capital and included backing from several major mortgage lenders and financial institutions. The company will use the funding to scale its AI agents across mortgage origination, automating tasks such as application reviews, underwriting decisions and closing-document checks. - learn more
    • MTech Capital led Nettle’s oversubscribed $4.8M seed round, with participation from Project A Ventures, Sure Valley Ventures, Portfolio Ventures and Ventures Together. The insurtech startup will use the funding to expand across the U.S. and Europe while growing its AI platform, which helps commercial insurers identify property risks, accelerate inspections and generate reports. - learn more
    • Bonfire Ventures doubled down on Santé by participating in the company’s $15M Series A, which was led by FINTOP and included other returning investors. The New York startup will use the funding to expand its AI-powered operating system for independent wine and liquor stores, which combines point-of-sale, e-commerce, payments, inventory and marketing tools in one platform. - learn more

    LA Exits

    • Winnow Solutions was acquired by Marina del Rey-based Spring Labs, with financial terms undisclosed. Winnow’s attorney-built library of more than 100,000 state and federal regulatory requirements will become a core part of SpringGRC, helping financial institutions connect changing laws directly to their compliance policies, controls and workflows. - learn more

      Download the dot.LA App

      LA Tech Week 2026: Sunday’s Event Lineup

      🔦 Spotlight

      LA Tech Week 2026 closes Sunday with one final day of events across Los Angeles. We have organized the remaining lineup by neighborhood so you can finish the week with a few last conversations before everyone returns to their regularly scheduled inboxes.

      ARTS DISTRICT

      12:00 PM

      CARSON

      12:00 PM

      CULVER CITY

      9:00 AM

      • Women in Cleantech & Sustainability Hike and Network: See Details Here
        Women in Cleantech & Sustainability

      6:00 PM

      • Founders pitch competition: See Details Here
        Biomorphix solutions, Nightingale regenerative

      HOLLYWOOD

      10:00 AM

      4:00 PM

      • AI International: Film, Music Video & Micro-Drama: See Details Here
        AI International Film Festivals

      MID CITY

      1:00 PM

      OTHER

      12:00 PM

      • ORGANIC LIFE LABS™ PRESENTS THE ALIGNMENT LAB: The Science of human performance: See Details Here
        The Blue Room Collective

      SANTA MONICA

      8:00 AM

      1:00 PM

      6:00 PM

      SOUTH LA

      2:00 PM

      • Future Builders : Family STEM Day: See Details Here
        Black L.A. Tech Week (Community Collective)

      VENICE

      10:00 AM

      12:00 PM

      • How to Raise Funds to Fund Any Business Using Digital Products.: See Details Here
        DN Events

      VIRTUAL

      5:00 PM

      WEST HOLLYWOOD

      3:00 PM

      Each session provides unique opportunities to gain insights, network, and explore various fields of tech innovation. For updates or more event information, visit the official Tech Week calendar.

      Download the dot.LA App

      LA Tech Week 2026: Saturday’s Event Lineup

      🔦 Spotlight

      LA Tech Week 2026 heads into the weekend Saturday with more opportunities to learn, meet fellow builders and explore what is being created across the region. Browse the day’s events by neighborhood below and find the gatherings worth leaving the house for.

      ARTS DISTRICT

      5:30 PM

      BEL AIR

      5:00 PM

      CULVER CITY

      10:00 AM

      1:00 PM

      4:00 PM

      DOWNTOWN

      11:00 AM

      2:00 PM

      • South Asians in Space, Physical AI: See Details Here
        american south asian network

      5:00 PM

      7:00 PM

      HOLLYWOOD

      8:00 PM

      INGLEWOOD

      10:00 PM

      LONG BEACH

      10:00 AM

      12:00 PM

      LOS FELIZ

      8:30 AM

      • Griffith Observatory Hike with Longevity Cities & Don't Die LA: See Details Here
        Longevity Cities

      MALIBU

      5:00 PM

      MARINA DEL RAY

      9:30 AM

      • The Brazen Capital Walk: Connecting Women, Capital & Opportunity: See Details Here
        BrazenEra

      6:00 PM

      • Build an AI workflow editor, natively in Angular: See Details Here
        Workflow Builder

      SANTA MONICA

      7:00 AM

      • Founders Running Club Run in Santa Monica: See Details Here
        Founders Running Club, MongoDb

      9:00 AM

      • MOLTEN - Spatial hackathon (ElevenLabs, AssemblyAI, Rokoko, Datafeel...): See Details Here
        Field Lab

      2:00 PM

      3:30 PM

      6:00 PM

      7:00 PM

      SOUTH LA

      7:00 PM

      THE VALLEY

      7:30 PM

      UCLA

      11:00 AM

      USC

      9:00 AM

      10:00 AM

      10:30 AM

      VENICE

      8:00 AM

      • Open Air Health Tech: See Details Here
        Open Air Health Tech, Bowshock, Govitamins App

      10:00 AM

      10:30 AM

      11:00 AM

      12:00 PM

      6:00 PM

      • Bots, Bytes & Bubbles Benefit: See Details Here
        Distinguished Minds Institute dba thinqueBytes®

      VIRTUAL

      9:00 AM

      • Ask a VP of Sales: Live GTM Office Hours for Early-Stage B2B Founders: See Details Here
        Kat Rucker Consulting Group

      11:00 AM

      WEST HOLLYWOOD

      11:00 AM

      • The 10x Engineer Showed Up. The 10x Organization Didn't.: See Details Here
        Workflow Builder, Tentaro

      3:00 PM

      WESTSIDE

      11:00 AM

      2:00 PM

      • Graphic Design & Digital Printing Meetup: See Details Here
        Big Frog Custom T-Shirts & More of West LA

      7:00 PM

      WESTWOOD

      12:00 PM

      Each session provides unique opportunities to gain insights, network, and explore various fields of tech innovation. For updates or more event information, visit the official Tech Week calendar.

      Download the dot.LA App

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