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XMeet the Startup That Wants To Deliver Ketamine to Your Door
David Shultz
David Shultz reports on clean technology and electric vehicles, among other industries, for dot.LA. His writing has appeared in The Atlantic, Outside, Nautilus and many other publications.
Ketamine is on the come up in the pharmaceutical world. Once confined to nightclubs and operating rooms, the drug is quickly gaining recognition as a valuable tool for treating mental health disorders including depression and anxiety.
Amid these rising tides, Wondermed has emerged, offering telehealth consultations and, potentially, the ability to deliver the drug right to your doorstep—all while building out a virtual platform and collecting data on how to use the molecule more effectively.
At the moment, the company provides a mail order service for courses of ketamine lozenges to those who’ve been prescribed the drug along with a telehealth software bridge between doctor and patient. Wondermed currently operates in five states — California, Texas, Florida, New York and Connecticut, though it plans to expand to another eight to 10 states in the next two weeks.
In the long run however, its plans are much bigger than being a link between doctors and patients.
“We generate more than 3,000 data points on every patient that comes into the funnel, and actually receives the medication,” says co-founder & Managing Director Jose Aycart.
His company is building out its online platform to collect and analyze patient data and provide mental health support services that may be useful, regardless of whether or not a patient is taking ketamine.
These data show in granular detail how ketamine therapies work. Does the route of administration matter? Does time of day matter? What types of patients are most likely to experience positive outcomes? It’s this data that represents the biggest business opportunity for Wondermed. The specifics of the monetization are still being worked out, but Aycart says it will never sell anonymized patient data to other companies.
Wondermed is in the midst of a seed funding round, targeting $7 million by the end of the month; It’s raised $5.6 million so far.
The company makes a bit of revenue by charging patients for consultations, but in the event that a patient doesn’t wind up using Wondermed’s platform, the consultation fee is refunded. For patients who are prescribed ketamine, the company charges only as much as the drugs cost them ($249 per month, which includes four doses), so neither Wondermed nor the physicians in its employ are incentivized to over-prescribe.
The drugs themselves are supplied by Tailor Made Compounding, a pharmacy in Nicholasville, Kentucky, and Wondermed is working on additional contracts in the pipeline with several other suppliers.
. Wondermed’s transformation comes as ketamine, which has typically been restricted to use as a general anesthetic, is quickly gaining recognition as a valuable tool for treating mental health disorders like depression and anxiety.
“What I’ve found interesting is how rapidly this field has emerged,” says Steven Grant, a drug and addiction researcher who spent 25 years at the National Institute on Drug Abuse and is now retired.

Ketamine is a simple organic molecule that first gained clinical popularity in the 1960s as an anesthetic. It produces a dissociative state in patients and dulls pain. Once in the bloodstream, the molecule travels to the brain where it binds to a protein called NMDA on the surface of neurons. NMDA has a variety of jobs, but it’s best-known for its role in learning, memory, and neuroplasticity—or the brain’s ability to form new pathways between neurons.
While the research into why ketamine is such an effective treatment for depression and anxiety is ongoing, the consensus so far is that the molecule’s power comes from this ability to rewrite or rewire the brain’s circuitry. If you’ve ever had an anxiety attack or a depressive episode, it can often feel like you’re stuck in a mental loop. Ketamine, it seems, offers a way to break that loop.
“It was this idea that you're increasing your neurological connections in the brain,” says Aycart. “You have the opportunity now to spark new forms of thought, new forms of emotion, or even new ideas.”
Unlike selective serotonin reuptake inhibitors (SSRIs) and other traditional drugs used to treat depression, ketamine’s effects are fast-acting—often appearing within minutes or hours of administration—and don’t require taking the drug daily.
“It really is revolutionary, and that’s why now more than ever, people are starting to get access to it, and companies like ourselves are really trying to bring it to people as an alternative form of medicine,” says Aycart.
Grant says the rise of ketamine clinics and telehealth services like Wondermed are likely a net positive because they increase patient access to drugs patients need, but he also has reservations about how the therapies are being applied.
Many of these psychoactive drugs—especially ketamine—are intended to be used in tandem with therapy, or at least under the supervision of a trained professional. Increasing the brain’s plasticity is a valuable tool for breaking out of depressive loops, but unless a professional is there to help the patient settle into a healthier mental pattern, the full benefits may be left on the table.
Wondermed offers a variety of supplementary support and strategies along with the drugs themselves, but taking advantage of these tools is left to the patient’s discretion. Grant would like to see a larger focus on extending and expanding that auxiliary support.
The company says it’s focused on building out the platform’s nonmedicinal mental health strategies—things like breathwork, meditation, music therapy—and adding them to an app. If they can get enough people on board, the eventual plan could be to sell health insights back to patients through a subscription model or something similar. They may even patent their own psychedelic molecules in the future. But all of this is likely quite a ways out.
“What we're trying to do is very new, and the landscape yet hasn't been built out,” says Aycart.
Clarification: This story has been updated to clarify Wondermed's monthly rate for ketamine lozenges.
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David Shultz
David Shultz reports on clean technology and electric vehicles, among other industries, for dot.LA. His writing has appeared in The Atlantic, Outside, Nautilus and many other publications.
Swipe Less, Know More, Build Faster: LA’s AI Push
10:25 AM | November 07, 2025
🔦 Spotlight
Happy Friday LA!
This week was about AI moving from side feature to core product strategy. Tinder is testing an opt-in “Chemistry” flow that learns your interests with permission, including signals from your camera roll, to propose fewer, higher quality matches. Snap is wiring Perplexity’s conversational, source linked answers directly into Snapchat. And Rivian spun out Mind Robotics to take the industrial AI it built for its own lines to a broader market.
Tinder Bets on AI for Quality Over Quantity
Tinder is piloting Chemistry, an opt-in experience that starts with a short Q&A and, with permission, analyzes cues from your camera roll to build a richer picture of what you like. The aim is to cut through swipe fatigue by presenting a smaller set of high intent matches each day, first in New Zealand and Australia, as part of Match Group’s larger 2026 product overhaul. The pitch is relevance and control, with phased rollout and consent front and center; if engagement lifts, expect tighter loops between real world signals and match recommendations.
Snap Brings Perplexity Answers into Snapchat
Snap struck a deal with Perplexity to deliver conversational, source linked results inside Snapchat starting in early 2026, backed by a one year cash and equity package reportedly worth about 400 million dollars. Ask a question where you already spend time and get a cited answer without hopping to a mobile browser, with Snap emphasizing that Snapchat data will not train Perplexity’s models. The announcement landed alongside improving fundamentals, signaling Snap’s plan to make trustworthy answers feel native to social habits rather than a separate destination.
Rivian Spins Out Mind Robotics
Rivian formed Mind Robotics to productize the software and systems that coordinate its own manufacturing, raising roughly 110 to 115 million dollars led by Eclipse. The goal is to sell factory floor intelligence beyond vehicles, including adaptive quality control, smarter material handling, and autonomous workflows that reduce downtime. With Rivian’s headquarters in Irvine and a growing regional robotics talent base, this puts Southern California on the map for next generation industrial automation tied to the EV supply chain.
Bottom line
LA’s tech scene is pushing AI toward measurable outcomes: better match quality, faster answers with clear citations, and more efficient production. Keep an eye on the unsexy details, including privacy choices and user consent, data boundaries between partners, and how each team turns these features into monetization. That is where this week’s announcements will turn into lasting advantage.
🤝 Venture Deals
LA Companies
- Evotrex exited stealth with a $16M Pre-A round led by Xstar Capital, with Unity Ventures, Kylinhall Partners, Vision Plus Capital, and founders of Anker Innovations participating; the capital will expand engineering and speed commercialization of its first product. The California startup plans to debut what it calls the world’s first power-generating RV trailer at CES 2026, designed to provide off-grid power and help extend EV range while towing. - learn more
- Zest AI, which provides AI-driven credit underwriting and lending intelligence for banks and credit unions, closed an oversubscribed, customer-led financing round from SchoolsFirst, Members 1st, ORNL, and Truliant credit unions, with participation from Citi Ventures. The company says the round came at a higher valuation than its prior growth raise and will fund more automation across the borrower journey and a broader rollout of LuLu, its generative AI lending-intelligence platform. - learn more
- Estate Media, the social first real estate media startup co-founded by “Million Dollar Listing” star Josh Flagg, says it has surpassed $6M in revenue and closed a $1M seed round, bringing total funding to $2.65M. New investors include Tinder co-founder Justin Mateen and real estate and media figures such as Samir Mezrahi (“Zillow Gone Wild”), Tracy Tutor, and Hudson Advisory, which the company says positions it for profitability and further growth. - learn more
LA Venture Funds
- Cedars Sinai Ventures joined Amae Health’s $25M Series B, led by Altos Ventures with participation from Quiet Capital, Bling Capital, Healthier Capital, and 8VC. The company, which is building an AI enabled clinic model for severe mental illness, says the funding will accelerate nationwide clinic openings, advance its AI care platform, and support research into conditions like schizophrenia, bipolar disorder, and treatment resistant depression. Total funding now tops $50 million. - learn more
- Magnify Ventures participated in MiSalud Health’s new funding round led by IGNIA, alongside Ulu Ventures, Redwood Ventures, Amplifica Capital, and client investor Taylor Farms. MiSalud, which delivers bilingual virtual and on-site care for blue-collar workforces, says the capital will help it expand into 20 new states and add services typically offered only in person; reports peg total funding at about $18.3 million. - learn more
- Alexandria Venture Investments participated in Accipiter Biosciences’ $12.7M seed round, which was co-led by Takeda and Flying Fish Partners. The Seattle startup is developing AI-designed de novo protein therapeutics that can combine multiple mechanisms in a single molecule, and it also announced partnerships with Pfizer and Kite Pharma alongside the financing. The company says the funds will advance preclinical programs in immunology and oncology and further build out its computational design platform. - learn more
- Rebel Fund participated in Cactus’s $7M seed round alongside Wellington Management, Y Combinator, and Pelion Venture Partners. Cactus builds a 24/7 AI copilot for home service businesses that answers calls, qualifies leads, books jobs, and manages follow ups to capture after hours demand. The company says the funding will support product expansion and go to market growth in the United States. - learn more
- B Capital joined the angel round for Microtide Biotechnology (also known as Weitao Bio), which raised over RMB 100 million, led by Qiming Venture Partners. The Shanghai company, spun out from Sile Biomedicine’s in vivo CAR T platform, is developing targeted LNP delivered in vivo CAR T therapies for blood cancers and autoimmune diseases, and will use the funds to advance its first candidate and further develop its core platform. - learn more
- Patron co led Flint’s $15M Series A, with participation from the USC Viterbi School of Engineering alongside Basis Set Ventures, AME Cloud Ventures, Afore Capital, and Y Combinator. Flint builds an AI platform that helps teachers personalize K 12 learning, and the company says the funding will accelerate product development and scale the service to more schools. - learn more
- Rebel Fund participated in Freya’s $3.5M round alongside Y Combinator, 212 VC, N1 Tech, BD Partners, and others. Freya is building voice automation tools that let companies create and manage natural language voice workflows, aiming to replace brittle IVR systems with more flexible, AI powered voice agents. The company says the funding will accelerate product development and early go to market efforts. - learn more
- Regeneration.VC led Hullbot’s roughly $10.6M Series A, with participation from Climate Tech Partners, Katapult Ocean, Folklore, Trinity Ventures, Rypples, NewSouth Innovations, and Bandera Capital. The Australian startup builds autonomous hull-cleaning robots that remove biofouling to cut ship fuel use and emissions, and it plans to use the funding to ramp manufacturing, expand global service hubs, and develop larger robotic platforms. - learn more
- M13 led Teleskope’s $25M Series A, with continued participation from Primary Venture Partners and Lerer Hippeau. Teleskope builds an agentic data security platform for the AI era, and says the capital brings total funding to $32.2M to accelerate product development and scale go to market. - learn more
- SmartGateVC participated in Coherence Neuro’s $10M seed round led by Topology Ventures and Artesian, alongside Blackbird, Possible Ventures, XEIA, Jumpspace, Divergent, Spacewalk VC, and others. San Francisco based Coherence Neuro is developing a closed-loop, bi-directional neurotechnology platform to treat cancers like glioblastoma by decoding and modulating electrical signals; the funding will support its first human trials and further product development. - learn more
- Rebel Fund participated in Mecha Health’s $4.1M seed round led by Valia Ventures, alongside Y Combinator, Reach Capital, and Phosphor Capital. Mecha Health is an applied AI lab that builds foundation models for radiology which read medical images and generate fully structured reports, and the new capital supports continued development and deployment of these systems. - learn more
LA Exits
- Green Econome was acquired by VCA Green, the sustainability practice of VCA Consultants. The Los Angeles firm is known for lifecycle strategies, building performance reporting, and compliance services like ENERGY STAR, LEED, CALGreen, and Title 24; combining it with VCA Green’s energy modeling, project management, and field verification creates a single team serving both new construction and existing buildings. Marika Erdely, Green Econome’s founder, is joining VCA Green as a principal. - learn more
- InData Consulting was acquired by The 20 MSP as part of a three-company deal that also included Red Level Group and iStreet Solutions. The additions expand The 20 MSP’s footprint in California, Arizona, Michigan, and the Sacramento area, bringing its total to 44 acquisitions in about three years. The company says it sources targets from its peer group to speed integrations and reduce attrition. - learn more
- Caulipower was acquired by Urban Farmer, a Paine Schwartz Partners portfolio company, creating a vertically integrated “better for you” frozen foods platform that pairs Urban Farmer’s manufacturing with Caulipower’s nationwide brand and distribution. Caulipower will continue operating under its name, with founder Gail Becker joining Urban Farmer’s board; financial terms were not disclosed. - learn more
- StudyOS was acquired by Sitero, a technology-enabled CRO, which simultaneously launched SiteroAI to position itself as the industry’s first fully AI-powered CRO. StudyOS’s Ash clinical-trial agent will be integrated with Sitero’s Mentor eClinical suite, with Sitero projecting 20–30% efficiency gains across the trial lifecycle beginning in 2026; terms were not disclosed. - learn more
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LA Is Betting on Nukes, Netflix and Next-Gen Attention
11:30 AM | December 19, 2025
🔦 Spotlight
Hey Los Angeles.
If you were looking for a quiet week, this was not it. LA is backing a portable nuclear reactor, Netflix just took a big step closer to owning Warner Bros. Discovery’s future, and Snapchat is basically handing the city a mirror and saying, “Here is what you did with your attention all year.”
Let’s dive in.
Radiant’s microreactors and LA’s new nuclear moment
Radiant Nuclear raised more than $300M in a Series D round to build Kaleidos, a one megawatt portable nuclear microreactor that is designed to roll off a factory line, ship in a standard container and replace diesel generators at remote sites, military bases and disaster zones. The new capital will fund a full scale test at Idaho National Lab and the build out of Radiant’s R 50 factory in Oak Ridge, Tennessee, which aims to produce up to 50 reactors a year starting later this decade.
For LA’s climate and infrastructure ecosystem, this is a big tell. The city that got rich on pipelines of content is now funding pipelines of electrons, betting that small, modular nuclear can be part of the grid story that powers everything from data centers to defense. It is a very different flavor of LA tech, but the pattern is familiar: take a frontier technology, wrap it in product thinking and try to make it feel as boring and reliable as a utility bill.
Netflix and Warner Bros. Discovery: one step closer
On the media front, Netflix just received an official recommendation from Warner Bros. Discovery’s board to proceed with the planned acquisition of WBD’s studios and streaming business. The board reaffirmed that the Netflix deal, which would fold Warner Bros. film and TV, HBO and HBO Max into Netflix, is in the best interest of shareholders, even as competing ideas swirl around what to do with the company.
Practically, this does not mean the deal is done. It means the process has moved from “big idea in a press release” into the slower, more serious phase of shareholder approvals and regulatory review. For Los Angeles, every incremental step like this reinforces the likely end state: a world where a handful of global platforms control not just distribution but also the studios and libraries that defined Hollywood’s last century.
Snapchat’s 2025 Recap and the attention economy in our backyard
Then there is Snapchat, which used its 2025 Recap to show off what its mostly Gen Z and Gen Alpha users actually did on the app this year. The company is leaning into personalized “year in review” stories that highlight top chats, memories, maps moments and creator content, while quietly reminding brands and investors that Snap still owns a very specific slice of youth attention that is hard to find anywhere else.
For LA, Snapchat’s recap is more than a cute end of year product. It is a reminder that some of the most important social infrastructure for the next generation is being built and iterated a short drive from Santa Monica Boulevard. While the grown ups argue about nuclear reactors and studio mergers, Snap is training the next wave of consumers how to communicate, create and remember their lives on a platform that barely existed fifteen years ago.
Taken together, this week says a lot about what “LA tech” means in 2025. On one end, you have Radiant trying to change how we power the physical world. On the other, Netflix and Snapchat are fighting over how we package and monetize the stories that live in our heads. Somewhere in the middle are the founders, investors and operators here who see all of this as raw material.Now keep scrolling for this week’s LA venture deals, fund announcements and acquisitions.
🤝 Venture Deals
LA Companies
- Fixated secured a $50M strategic investment from Eldridge Industries to fuel what it calls the “next era of creator-led empires.” The company says the capital will help it expand its capabilities and partnerships that support creators in building and scaling their own brands and businesses beyond traditional sponsorship deals. - learn more
- Vital Lyfe raised $24M in financing, including more than $18M in seed funding, in a round led by Interlagos and General Catalyst with participation from Generational Partners, Cantos, Space.VC and Also Capital. The Hawthorne based startup, founded by former SpaceX engineers, will use the capital to ramp manufacturing of its portable, autonomous “water making” systems, expand early deployments with partners like maritime operators and NGOs, and prepare for its first consumer ready products in 2026. - learn more
- Molly Sims’ YSE Beauty closed a $15M Series A growth equity round led by Silas Capital, with participation from L Catterton and existing backers Willow Growth Partners and Halogen Ventures. The clinically tested skincare brand, which targets women 35+ and recently rolled out nationally at Sephora, will use the funding to fuel product development, expand across Sephora doors in the U.S., and grow its direct-to-consumer e-commerce business. - learn more
- Ember LifeSciences raised a $16.5M Series A led by Sea Court Capital, with participation from Cardinal Health, Carrier Ventures and other strategic investors including former U.S. Secretary of State Mike Pompeo. The Los Angeles based cold chain tech company will use the funding to launch its next generation Ember Cube 2 shipping system and expand globally, helping pharma and healthcare customers cut temperature related losses and waste in medicine distribution. - learn more
- Strada, a Los Angeles–based media collaboration startup, received a strategic investment from Other World Computing (OWC) to accelerate its product roadmap. The company’s peer-to-peer platform lets video pros access, share and review large files directly from local drives anywhere in the world, without uploading to the cloud. The partnership will also include co-marketing efforts, joint NAB 2026 presence, and bundled offerings that pair Strada’s software with OWC’s storage and workflow hardware. - learn more
LA Venture Funds
- Calibrate Ventures participated in Manifold’s Series B round, backing the company as it scales its AI technology platform. Manifold plans to use the new capital to accelerate product development, deepen its capabilities for enterprise customers, and grow its team to support broader commercial rollout. - learn more
- SmartGateVC participated in NeuraWorx’s oversubscribed seed round, which was led by Nexus NeuroTech to back the company’s neurotechnology based therapies for central nervous system (CNS) disorders. NeuraWorx plans to use the capital to advance its R&D and early clinical work, build out its technology and product pipeline, and expand its team as it moves toward bringing new CNS treatments to market. - learn more
- Kinship Ventures participated in Lovable’s $330M Series B, which values the Stockholm based “vibe coding” platform at $6.6B in a round co-led by CapitalG and Menlo Ventures’ Anthology fund. The company lets non developers build full stack software from natural language prompts, and says it will use the new capital to scale its AI native platform globally, deepen enterprise features and integrations, and support a fast growing base of business users building production apps on Lovable. - learn more
- B Capital participated in MoEngage’s $180M Series F follow-on, which brings the customer engagement platform’s total Series F raise to $280M. The round was led by ChrysCapital and Dragon Funds, with Schroders Capital and TR Capital also joining, and will be used to accelerate MoEngage’s Merlin AI product roadmap, expand go-to-market teams across North America and EMEA, and pursue strategic acquisitions while also funding an employee and early-investor liquidity program. - learn more
- O'Neil Strategic Capital led HEN Technologies’ $22M financing, which combines a $20M oversubscribed Series A with $2M in venture debt, to build what the company calls the industry’s first operating system for fire defense. The Hayward based startup will use the capital to scale its IoT enabled hardware and Fluid IQ predictive AI platform, capture a comprehensive operational fire dataset, and expand global deployments with distributors and agencies as it aims to make fire suppression faster, more efficient and data driven. - learn more
- Core Innovation Capital participated in Transparency Analytics’ second funding round, backing the company alongside lead investor Deciens Capital, Allianz Life Ventures, Mouro Capital, FJ Labs and SUM Ventures. Transparency Analytics, which provides quantitative, tech enabled credit ratings and benchmarking for private credit, will use the funding to scale its platform, refine go to market strategy and build out products like its private credit index as the asset class grows. - learn more
- Upfront Ventures participated in Nanit’s $50M growth round, which was led by Springcoast Partners with support from JVP. The company will use the funding to expand its AI powered Parenting Intelligence System and related tools that give parents real time, personalized insight into a baby’s sleep, health and development between pediatric visits. - learn more
- Integrity Growth Partners fully funded Fluency’s $40M Series A, coming in as the company’s first major institutional investor. Fluency, a “digital advertising operating system,” centralizes and automates paid media across Google, Meta, TikTok, programmatic and more, already powering nearly $3B in annual ad spend and over 250,000 monthly campaigns. The company plans to use the capital to enhance its automation and agentic AI capabilities, expand integrations with publishers and tech partners, and grow its team. - learn more
- JAM Fund joined Last Energy’s oversubscribed $100M+ Series C, backing the advanced nuclear startup as it pushes to commercialize its factory built microreactors. The round was led by Astera Institute with investors including Gigafund, The Haskell Company, AE Ventures, Ultranative, Galaxy Interactive and Woori Technology. Last Energy plans to use the capital to complete its PWR-5 pilot reactor under the U.S. DOE’s Reactor Pilot Program, ramp manufacturing in Texas, and advance its larger PWR-20 units toward commercial deployment in the U.S. and U.K. - learn more
LA Exits
- NextWave is being acquired by Pattern, bringing the TikTok-focused commerce agency under Pattern’s umbrella to strengthen its TikTok Shop and creator-led commerce capabilities. The deal folds NextWave’s expertise in TikTok Shop strategy, operations and creator partnerships into Pattern’s broader ecommerce platform, giving brands a single partner to manage marketplace, DTC and social shopping channels. - learn more
- Ubiquitous is being acquired by Humanz as part of Humanz’s broader push to build a next-gen, data driven creator economy platform alongside its recently announced $15M funding round. The deal folds Ubiquitous’ creator marketing and TikTok/native social expertise into Humanz’s influencer analytics and campaign tooling, giving brands a more end-to-end partner for strategy, creator management and performance measurement across major social channels. - learn more
- Silver Tribe Media is being acquired by TPG-backed Initial Group, which is folding the company into its broader sports and entertainment platform. The deal brings Silver Tribe’s storytelling, production and athlete brand work under Initial Group’s umbrella, giving it more capital and distribution while expanding Initial’s in-house content capabilities around teams, athletes and sponsors. - learn more
- Duffl, the YC-backed campus delivery startup, is being acquired by Rev Delivery, bringing its “10M campus delivery pioneer” operation under Rev’s umbrella. The acquisition folds Duffl’s college-focused, ultra-fast delivery network and playbook into Rev’s hyper-growth delivery operators, with the goal of scaling on-demand service across more campuses and strengthening Rev’s position in student-centered last-mile logistics. - learn more
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