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XMeet the Startup That Wants To Deliver Ketamine to Your Door
David Shultz
David Shultz reports on clean technology and electric vehicles, among other industries, for dot.LA. His writing has appeared in The Atlantic, Outside, Nautilus and many other publications.
Ketamine is on the come up in the pharmaceutical world. Once confined to nightclubs and operating rooms, the drug is quickly gaining recognition as a valuable tool for treating mental health disorders including depression and anxiety.
Amid these rising tides, Wondermed has emerged, offering telehealth consultations and, potentially, the ability to deliver the drug right to your doorstep—all while building out a virtual platform and collecting data on how to use the molecule more effectively.
At the moment, the company provides a mail order service for courses of ketamine lozenges to those who’ve been prescribed the drug along with a telehealth software bridge between doctor and patient. Wondermed currently operates in five states — California, Texas, Florida, New York and Connecticut, though it plans to expand to another eight to 10 states in the next two weeks.
In the long run however, its plans are much bigger than being a link between doctors and patients.
“We generate more than 3,000 data points on every patient that comes into the funnel, and actually receives the medication,” says co-founder & Managing Director Jose Aycart.
His company is building out its online platform to collect and analyze patient data and provide mental health support services that may be useful, regardless of whether or not a patient is taking ketamine.
These data show in granular detail how ketamine therapies work. Does the route of administration matter? Does time of day matter? What types of patients are most likely to experience positive outcomes? It’s this data that represents the biggest business opportunity for Wondermed. The specifics of the monetization are still being worked out, but Aycart says it will never sell anonymized patient data to other companies.
Wondermed is in the midst of a seed funding round, targeting $7 million by the end of the month; It’s raised $5.6 million so far.
The company makes a bit of revenue by charging patients for consultations, but in the event that a patient doesn’t wind up using Wondermed’s platform, the consultation fee is refunded. For patients who are prescribed ketamine, the company charges only as much as the drugs cost them ($249 per month, which includes four doses), so neither Wondermed nor the physicians in its employ are incentivized to over-prescribe.
The drugs themselves are supplied by Tailor Made Compounding, a pharmacy in Nicholasville, Kentucky, and Wondermed is working on additional contracts in the pipeline with several other suppliers.
. Wondermed’s transformation comes as ketamine, which has typically been restricted to use as a general anesthetic, is quickly gaining recognition as a valuable tool for treating mental health disorders like depression and anxiety.
“What I’ve found interesting is how rapidly this field has emerged,” says Steven Grant, a drug and addiction researcher who spent 25 years at the National Institute on Drug Abuse and is now retired.
Ketamine is a simple organic molecule that first gained clinical popularity in the 1960s as an anesthetic. It produces a dissociative state in patients and dulls pain. Once in the bloodstream, the molecule travels to the brain where it binds to a protein called NMDA on the surface of neurons. NMDA has a variety of jobs, but it’s best-known for its role in learning, memory, and neuroplasticity—or the brain’s ability to form new pathways between neurons.
While the research into why ketamine is such an effective treatment for depression and anxiety is ongoing, the consensus so far is that the molecule’s power comes from this ability to rewrite or rewire the brain’s circuitry. If you’ve ever had an anxiety attack or a depressive episode, it can often feel like you’re stuck in a mental loop. Ketamine, it seems, offers a way to break that loop.
“It was this idea that you're increasing your neurological connections in the brain,” says Aycart. “You have the opportunity now to spark new forms of thought, new forms of emotion, or even new ideas.”
Unlike selective serotonin reuptake inhibitors (SSRIs) and other traditional drugs used to treat depression, ketamine’s effects are fast-acting—often appearing within minutes or hours of administration—and don’t require taking the drug daily.
“It really is revolutionary, and that’s why now more than ever, people are starting to get access to it, and companies like ourselves are really trying to bring it to people as an alternative form of medicine,” says Aycart.
Grant says the rise of ketamine clinics and telehealth services like Wondermed are likely a net positive because they increase patient access to drugs patients need, but he also has reservations about how the therapies are being applied.
Many of these psychoactive drugs—especially ketamine—are intended to be used in tandem with therapy, or at least under the supervision of a trained professional. Increasing the brain’s plasticity is a valuable tool for breaking out of depressive loops, but unless a professional is there to help the patient settle into a healthier mental pattern, the full benefits may be left on the table.
Wondermed offers a variety of supplementary support and strategies along with the drugs themselves, but taking advantage of these tools is left to the patient’s discretion. Grant would like to see a larger focus on extending and expanding that auxiliary support.
The company says it’s focused on building out the platform’s nonmedicinal mental health strategies—things like breathwork, meditation, music therapy—and adding them to an app. If they can get enough people on board, the eventual plan could be to sell health insights back to patients through a subscription model or something similar. They may even patent their own psychedelic molecules in the future. But all of this is likely quite a ways out.
“What we're trying to do is very new, and the landscape yet hasn't been built out,” says Aycart.
Clarification: This story has been updated to clarify Wondermed's monthly rate for ketamine lozenges.
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David Shultz
David Shultz reports on clean technology and electric vehicles, among other industries, for dot.LA. His writing has appeared in The Atlantic, Outside, Nautilus and many other publications.
No Tipping Necessary: Hundreds of Delivery Robots Are Coming to Los Angeles
07:59 AM | January 13, 2021
On a recent crisp winter morning outside an empty office park in the San Fernando Valley, there were no workers to be seen. That is unless one counts the cooler-sized delivery robot slowly whirring down the sidewalk as Felipe Chavez, founder and CEO of Kiwibot, nervously watched to make sure the droid did not veer of course.
Just as no one now thinks twice about seeing e-scooters that were non-existent before late 2017, the sight of a robot ferrying salads, pizza, or groceries could become common on Los Angeles sidewalks before this year is over.
Kiwibot has quietly been testing its robots – specially designed to look cute and non-threatening – for the past few weeks in the Valley, as well as more recently at a major university campus the company won't yet name. If all goes well, Kiwibot will begin offering delivery to students through as early as next month before expanding to Santa Monica and other parts of the city after that.
"L.A. is going to be our most important city this year," Chavez said. "In the first five months of the year we plan to employ 100 robots here in the city, and we expect that by the end of the year we're going to have around 400 robots deployed."
Postmates, which is now owned by Uber, has been testing a handful of delivery robots in West Hollywood since April. While those are accompanied by a human chaperone, the Kiwibot robots set out on their own, though operators take over remotely for more complex tasks like crossing the street.
Kiwibot has already made over 120,000 deliveries since 2017 during rollouts at University of California, Berkeley, University of Denver, and San Jose, where it partnered with Shopify and Ordermark. But L.A., with its vast geographic footprint, is a whole new degree of difficulty.
"It's a great challenge for us," said Chavez.
Kiwibot chose L.A. because the city already has a high adoption of food delivery, it is home to potential partners like ChowNow and Ordermark, and the city has been a willing collaborator through its Urban Movement Labs (UML), mostly by sharing data on city streets and sidewalks.
"We trust L.A. to be the best new market for us because the food delivery habit is already there, and we feel backed to scale in an organized and socially responsible and sustainable manner," said David Rodriguez, Kiwibot's head of business.
After a confrontational approach between cities and ridesharing and e-scooter companies, Lilly Shoup, UML's interim executive director, says L.A. is trying to be more collaborative with delivery robots.
"I think we've learned that it's important for city transportation agencies to get ahead of new technology before they appear on city streets," Shoup said. "It's important to understand their business models and proactively develop policies."
UML is also working on a pilot to deliver goods via drone by 2022 and in both instances Shoup says the technology can help reduce pollution and congestion since most deliveries now are made via cars.
"It's really exciting to think about new ways to reduce the environmental impact of delivery," Shoup said.
Robots substantially bring down the cost of delivery, which could help restaurants that operate on thin margins during even the best of times and have been devastated this year. But it will also mean fewer delivery jobs, most of which have been preserved as contract work in California with the recently passed Proposition 22.
Restaurants typically pay between 15% to 30% on orders placed with delivery services like Postmates or Grubhub and drivers are hardly getting rich. In fact, they often make less than minimum wage.
Kiwibot charges fees of a couple dollars on each order – which can be absorbed by the restaurant or passed onto customers. The company says its cost per delivery is now $2.98 but as it scales and the technology improves it can shave the cost down to $1.23 by the end of 2022.
Right now, Kiwibot robots – which cost between $2,500 and $4,000 each – can only operate in a 1.5 mile radius but the company's next generation can go eight miles and is large enough to fit a 12-inch pizza.
Will the Public Accept Robots?
Even when the technology is ready, Kiwibot has what may be a tougher obstacle to overcome – public acceptance. Public safety commissioners in West Hollywood raised concerns about Postmates' robots and even in tech-friendly San Francisco, a city lawmaker, worried they might run into pedestrians, tried to ban them.
Kiwibot warns potential investors on its crowdfunding page: "Delivery bots have proved controversial in some regulatory environments with some cities, like San Francisco, putting out laws that make it difficult for us to deploy. If this became widespread we would have trouble going to market."
Chavez says he spends a great deal of time thinking about how he can get the public to be comfortable with robots.
"There is a sector of people that are concerned about robots and I think that it is very important to listen to them and to get their feedback on everything. but robots are going to happen," Chavez said.
The robot also has a sign affixed to the back to clarify that it is not recording any video, something that was added after homeless people in San Jose feared they were being spied on.
There is a "black box," which records in case of an emergency, but none of the devices have been stolen — so far.
Even though local regulations can allow for robots to go as fast as 10 mph, Chavez has found a speed of 6 mph makes people feel safer.
There are also important visual considerations. Kiwibot's robots look nothing like the hulking devices conjured up in sci-fi movies like "Transformers" or "The Terminator." They are more like a plastic cooler on wheels with lights on the front that resemble a smiling face.
"The new version is even more cute," said Chavez. "It's like a squirrel on a rock."
Taking a page from nature, the design is deliberately playful and small.
"When you see an animal and it is bigger than the width of your shoulders you feel threatened," Chavez said. "So we have made sure that the robot is never going to be wider [than you] so that people don't feel threatened."
Coronavirus has also been helpful, helping accelerate the adoption not only of delivery but also of robots – who you don't have to worry about coughing on you.
Competition with Bigger Robot Deliveries
Kiwibot, which is based in San Jose, has raised more than half $1 million from more than 650 investors in its latest crowdfunding campaign, to bring its fundraising total to over $3 million.
That pales in comparison to not only Uber but also much larger rivals Starship, a robot food delivery service launched in 2014 by two Skype co-founders that plans to rollout deliver to 100 universities by next summer and Nuro – an autonomous vehicle startup founded by two ex-Google engineers valued at $4 billion. The company received regulatory approval last week to operate on city streets in the Bay Area.
But with global autonomous last-mile delivery projected to grow from $11.16 billion next year to $76 billion by 2030, Kiwibot sees room for multiple competitors.
"In L.A. right now we are talking with multiple partners, very big companies," said Chavez.
"Everything is moving very fast," he added, as his robot inched along the sidewalk, heading back to the lab to continue more testing.
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Ben Bergman
Ben Bergman is the newsroom's senior finance reporter. Previously he was a senior business reporter and host at KPCC, a senior producer at Gimlet Media, a producer at NPR's Morning Edition, and produced two investigative documentaries for KCET. He has been a frequent on-air contributor to business coverage on NPR and Marketplace and has written for The New York Times and Columbia Journalism Review. Ben was a 2017-2018 Knight-Bagehot Fellow in Economic and Business Journalism at Columbia Business School. In his free time, he enjoys skiing, playing poker, and cheering on The Seattle Seahawks.
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ben@dot.la
🛡️Meet the Defense Unicorn That Just Raised $250M to Stop Drone Swarms
11:19 AM | March 07, 2025
🔦 Spotlight
Hello, Happy Friday!
For this week's spotlight story, we're turning our attention to a monumental leap in defense technology achieved by Epirus, a dynamic startup based in Torrance that specializes in groundbreaking anti-drone systems. Recently, Epirus successfully secured a whopping $250 million in Series D funding, raising its total capital to over $550 million and solidifying its status as a unicorn in the defense tech sector.
Image Source: Epirus
At the heart of Epirus’s arsenal is Leonidas, a solid-state, directed energy system named after the fierce Spartan king. As formidable as its namesake suggests, Leonidas stands out by neutralizing unmanned systems and other electronic threats with unmatched precision—a vital capability in today’s digital battlefield where drones are increasingly common. Offering a high-tech shield against potential threats, Leonidas has established Epirus as a key player in modern warfare technology, underscored by significant contracts such as a notable $66 million deal with the U.S. Army in 2023.
Founded in 2018 by a visionary team including Joe Lonsdale, Bo Marr, Max Mednik, Nathan Mintz, Grant Verstandig, and John Tenet, Epirus combines expertise across technology, strategy, and security to push the boundaries of defense innovation. The collective experience and strategic foresight of its founders have propelled the company's rapid growth and technological advancements.
Looking to the future, Epirus plans to utilize this influx of capital to broaden its reach into international and commercial markets, enhance its team, fortify its supply chain, and establish a new training center in Oklahoma to further military preparedness.
This latest round of funding was led by 8VC and Washington Harbour Partners LP, accompanied by a diverse group of new and returning investors, including strategic defense partner General Dynamics Land Systems and seasoned investors like StepStone Group and T. Rowe Price Investment Management, Inc. New stakeholders such as Oppenheimer's Private Market Opportunities Vista VI Fund, NightDragon, Manhattan Venture Partners, Centaurus Capital LP, and Center15 Capital also joined, reflecting robust market confidence in Epirus’s innovative approach and future potential.
Keep an eye on Epirus as it navigates this exciting phase of growth and innovation. With its advanced technologies and strategic expansions, Epirus is not just responding to the challenges of today’s digital battlefield but is also setting the pace for tomorrow’s defense landscape.
🤝 Venture Deals
LA Companies
- Zeitview, a Los Angeles-based leader in AI-powered infrastructure inspections, has raised a $60M funding round led by Climate Investment, with participation from Upfront Ventures and others. The funds will be used to accelerate the development of its Visual AI technology and enhance its Insights software platform, supporting infrastructure sectors such as solar, wind, utilities, properties, and telecom throughout the asset lifecycle. - learn more
- Nervonik, a medical device company specializing in peripheral nerve stimulation for chronic pain relief, has raised a $13M Series A funding round led by U.S. Venture Partners (USVP). The funds will be used to advance the development of its next-generation nerve stimulation technology, aiming to provide effective, non-opioid pain management solutions. - learn more
- Mote, a company specializing in carbon-negative energy production, has secured $7M in the initial close of its Series A funding round. The investment was co-led by Nella Next and Preston-Werner Ventures. Mote converts agricultural and forestry waste into clean hydrogen through its Biomass Carbon Removal and Storage (BiCRS) technology, which also sequesters carbon dioxide. The funds will be used to advance its first commercial-scale facility, expand engineering capabilities, and accelerate strategic partnerships in the hydrogen and energy sectors. - learn more
- FastLane Labs, a developer of Maximal Extractable Value (MEV) infrastructure, has raised a $6M funding round led by Figment Capital and DBA. The funds will be used to develop a comprehensive liquid staking token on the Monad blockchain, aiming to build a sustainable MEV ecosystem that benefits users, decentralized applications (dApps), and stakers. - learn more
- Supergut, a company specializing in gut health products like powders, bars, and shakes containing resistant starches and prebiotic fibers, has secured a significant growth equity investment led by Full Frame Growth Partners, with participation from Alpha Edison, Rocana Venture Partners, Strand Equity Partners, and others. The funds will support new product innovation, retail expansion, and new hires. Additionally, Supergut has appointed Tracey Warner Halama, former CEO of Vital Proteins, as its new CEO to lead this next phase of growth. The company has experienced a 172% sales increase in 2024, driven by its 'GLP-1 booster' product. - learn more
- FairPlay, a Fairness-as-a-Service company, has raised a $10M funding round from Infinity Ventures, JPMorgan Chase, and Nyca Partners. FairPlay specializes in developing tools that help organizations identify and correct biases in their AI-driven decision-making processes, aiming to promote fairness and compliance in sectors like financial services and insurance. The company plans to use the funds to expand its operations and enhance its product offerings, furthering its mission to build fairness infrastructure for the internet and ensure safer AI adoption. - learn more
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- MelodAI, a company specializing in AI-generated content (AIGC) and multimodal AI agent services, has secured a new round of funding led by LF Labs. The funds will be used to advance product development and expand market presence in the Web3 and AI entertainment sectors, enhancing MelodAI's competitiveness in the global AIGC and AI agent service industries. - learn more
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- Fika Ventures led a $4.7M Seed funding round for Outmarket AI, a San Francisco-based intelligence platform designed to transform commercial insurance through AI-powered insights and automation. The funds will be used to accelerate platform innovation, expand the team, and establish strategic partnerships with leading brokers and carriers. - learn more
- FirstLook Partners participated in a $25M equity funding round for Flex, a Miami-based fintech company that provides an all-in-one finance platform for business owners. Flex offers services such as business banking, expense management, credit cards, and accounts payable automation. The company plans to use the funds to enhance its AI-driven accounts payable automation and expand its personal finance management services for business owners. - learn more
- B Capital led a $96M equity investment in Odeko, a New York-based all-in-one operations and technology partner for local coffee shops, cafes, and other food and beverage businesses. Including a $30M credit facility from Banc of California, the total funding amounts to $126M. Odeko plans to use the funds to fuel growth through new services and cost savings for customers, acquire businesses to extend its market reach and product offerings, and build out its leadership team. - learn more
- Presight Capital participated in a $2.2M Seed funding round for Needle, an AI-powered search and agent development platform based in San Francisco and Berlin. Needle enables organizations to access and manage data across various internal systems, integrating with tools like Confluence, Slack, Gmail, and Dropbox. The funds will be used to expand the engineering team, enhance core technology, and accelerate go-to-market initiatives. - learn more
- Village Global participated in a $2.8M Pre-seed funding round for Orpheus Ocean, a New Bedford, Massachusetts-based company specializing in deep-sea robotics. Orpheus Ocean develops autonomous underwater vehicles (AUVs) designed to enhance deep ocean and seafloor data collection. The funds will be used to conduct the first commercial demonstrations of their AUV technology, expand their technical team, and grow their fleet to support increased deployments in the coming year. - learn more
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